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On the front cover: Molecular dynamics involved in DNA compaction

DNA is packaged in the cell nucleus by wrapping around proteins called histones to form chromatin fibers. Nucleosomes, the structural units of these fibers, are formed by wrapping 146 base pairs of DNA around eight histones. Additional histone proteins, known as linker histones, bind to nucleosomes in a 1:1 ratio to form chromatosomes.  The study…

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HITS and Yale: Over the ocean, across the Universe

Start of the HITS-Yale program in astrophysics – the collaboration comprises two postdoctoral fellowships as well as regular meetings in Heidelberg and New Haven The Heidelberg Institute for Theoretical Studies (HITS) and Yale University, New Haven/U.S, have started a joint initiative to foster collaboration between astronomers and astrophysicists on both sides of the ocean: the…

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Made by nature: a highly elastic pressurized balloon

Collagens constitute the dominant class of extracellular proteins in multicellular organisms. They are highly abundant wherever high elasticity is needed. The collagens of cnidarians, multicellular organisms among the oldest appearing on Earth and including jellyfish and sea anemones, are particularly fascinating. They structure the wall of the nematocyst, a balloon-shaped organelle, designed to naturally withstand…

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Volker Springel elected to the German Academy of Sciences “Leopoldina”

Volker Springel, head of the Theoretical Astrophysics group at the Heidelberg Institute for Theoretical Studies (HITS), has been elected to the German Academy of Sciences Leopoldina. He will be invited to present a lecture and receive his membership certificate at the official inauguration ceremony in March 2017. The astrophysicist Prof. Volker Springel has designed and…

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HITS Annual Report: Advanced Research

Annual Report of the Heidelberg Institute for Theoretical Studies (HITS) published: Advanced research using supercomputers – from molecular biology to astrophysics. In 2010, the physicist Klaus Tschira (1940 – 2015) and the Klaus Tschira Foundation founded the Heidelberg Institute for Theoretical Studies (HITS). Today, around 120 scientists from 22 countries work at the non-profit research…

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Not only the Weather: Workshop on Advances in Economic Forecasting

When we are talking about forecasting, most of us associate it with the weather, come rain or shine. However, forecasting is also a big issue in the economic sector, where forecasts inform the decisions of policymakers, businesses and consumers alike. On June 6, 2016, the Computational Statistics (CST) group at HITS (group leader: Prof. Tilmann…

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Call for Proposals for Genomic Information Compression and Storage

MPEG Issues Genomic Information Compression and Storage Joint Call for Proposals in Conjunction with ISO/TC 276/WG5 The introduction of high-throughput DNA sequencing has led to the generation of large quantities of genomic data and related information that have to be stored, transferred and analyzed. To handle these massive amounts of genomic data technologies are developed…

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