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SHORT CV 2010 - present: PostDoctoral researcher on the Virtual Liver Network. 2009: 2 month visit to work in the laboratory of Prof. Michael Shirts at the University of Virginia funded by a CCPB USPA travel award 2006 - 2010: PhD study at University of Leeds, supervised by Richard Jackson. Thesis title: Computational approaches for drug design at the Protein-Protein interface 2005: BBSRC Summer Studentship, supervised by Prof. Sir Tom Blundell and Dr. David Burke2003 - 2006: St Annes College, University of Oxford, BA Physics. RESEARCH INTERESTS I am interested in biomolecular association. During my PhD this was primarily focussed on questions regarding the concept of how 'druggable' a pocket on a protein surface might be, and on performing alchemical free-energy calculations on small-molecule mimetics of a helical portion of the p53 protein that regulates apoptosis via binding to a pocket on the hDM2 protein. In the Wade lab I am working on the Virtual Liver Network, where I am applying brownian dynamics simulations of proteins that associate to lipid membranes. I am continuing to maintain access to the Q-SiteFinder program that was previously developed in the Jackson lab. Please contact me if you have any suggestions for further developments or features that you would like to see. PUBLICATIONS Pubmed PERSONAL INTERESTS Mountain-biking, White-water kayaking, cross-country skiing and learning german! |
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