On January 1st 2019 the Horizon2020 Coordinating and Support Action “EU-STANDS4PM – A European standardization framework for data integration and data-driven in silico models for personalized medicine” launched activities with support by the European Commission Directorate-General for Research and Innovation. During the next three years EU-STANDS4PM will initiate an EU-wide mapping process to assess and evaluate strategies for data-driven in silico modelling approaches. A central goal is to develop harmonized transnational standards, recommendations and guidelines that allow a broad application of predictive in silico methodologies in personalized medicine across Europe.

Metabolic signaling as new concept for breast cancer risk estimation

HITS is partner of the international research consortium “MESI-STRAT” that explores the interplay of breast cancer metabolism and oncogenic signaling by systems medicine. The consortium was awarded by the European Union €6 million for five years. The main goal of the five-years project is to develop new models for knowledge-based stratification of patients into subgroups to guide targeted interventions. The Scientific Databases and Visualization (SDBV) group at HITS takes care of the model and data management platform.


The “German Network for Bioinformatics Infrastructure-de.NBI” is a national, academic and non-profit infrastructure supported by the German Federal Ministry of Education and Research (BMBF) providing bioinformatics services to users in life sciences research and biomedicine in Germany and Europe. The de.NBI program was launched by the BMBF in March 2015 and the ELIXIR Node in…


The subject of FAIRDOM is data management services for systems biology for projects within the ERASysAPP ERANet funding initiative and beyond. In the course of the ERA-Net EraSysAPP and European research infrastructure project ISBE, three national funding agencies support a Data and Model Management Project – FAIRDOM (Findable Accessible Interoperable Reusable Data Operations, and Models).…

SABIO-RK database

Biochemical Reaction Kinetics Database SABIO-RK ( is a curated database containing structured information about biochemical reactions and their corresponding kinetics. It describes participants and modifiers of the reactions, as well as measured kinetic data (including kinetic rate equations) embedded in their experimental and environmental context. The system offers standardized data for metabolic and newly also…