{"id":1400,"date":"2014-10-21T18:23:15","date_gmt":"2014-10-21T16:23:15","guid":{"rendered":"http:\/\/www.h-its.org\/?page_id=1400"},"modified":"2021-06-22T12:35:46","modified_gmt":"2021-06-22T10:35:46","slug":"projekte","status":"publish","type":"page","link":"https:\/\/www.h-its.org\/de\/forschung\/mbm\/projekte\/","title":{"rendered":"Projekte"},"content":{"rendered":"\n

Aktuelle Projekte<\/h2>\n\n\n
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\n \"Diffusion_Models\" <\/div>\n
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Diffusion models for protein design<\/p>\n

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15.10.2024<\/div>\n <\/div>\n

Generatives Deep Learning hat das Proteindesign ver\u00e4ndert und erm\u00f6glicht die Entwicklung neuer Proteinstrukturen, Interaktionen und Funktionen mit hoher Pr\u00e4…<\/p>\n Mehr erfahren<\/a>\n <\/div>\n<\/div>\n \n

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\n \"\" <\/div>\n
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Mechanoradicals and DOPA in Collagen Tissue<\/p>\n

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13.12.2021<\/div>\n <\/div>\n

– A role for dihydroxyphenylalanine (DOPA) as a marker of mechanical stress and radical scavenger in collagen – Collagen is responsible for the …<\/p>\n Mehr erfahren<\/a>\n <\/div>\n<\/div>\n \n

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\n \"\" <\/div>\n
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Mechanokinases<\/p>\n

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12.03.2021<\/div>\n <\/div>\n

Kinases are abundantly present in all cells and involved in the regulation of many important processes, such as cell survival, growth, …<\/p>\n Mehr erfahren<\/a>\n <\/div>\n<\/div>\n \n

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\n \"\" <\/div>\n
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Simulations of Collagen Failure and Mechanoradicals<\/p>\n

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12.03.2021<\/div>\n <\/div>\n

It has been known for many decades that synthetic polymers subjected to mechanical stress generate mechanoradicals by rupture of chemical bonds. …<\/p>\n Mehr erfahren<\/a>\n <\/div>\n<\/div>\n \n

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\n \"\" <\/div>\n
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Intrinsically disordered Proteins<\/p>\n

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12.03.2021<\/div>\n <\/div>\n

Intrinsically disordered proteins (IDPs) are a new class of proteins that lack secondary and tertiary structures and instead explore a broad …<\/p>\n Mehr erfahren<\/a>\n <\/div>\n<\/div>\n \n

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\n \"\" <\/div>\n
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Force-triggered blood coagulation<\/p>\n

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30.01.2020<\/div>\n <\/div>\n

Von Willebrand factor (VWF) is a giant multidomain extracellular blood protein in charge of a key adhesive process during hemostasis: the …<\/p>\n Mehr erfahren<\/a>\n <\/div>\n<\/div>\n \n <\/div>\n\n <\/div>\n\n\n\n

Abgeschlossene Projekte<\/h2>\n\n\n
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\n \"\" <\/div>\n
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Emulation in simulation<\/p>\n

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28.06.2021<\/div>\n <\/div>\n

„Emulation in Simulation“ verbindet die HITS-Expertise in computergest\u00fctzter Statistik und numerischer Simulation, um eine neue Generation von Werkzeugen f\u00fcr …<\/p>\n Mehr erfahren<\/a>\n <\/div>\n<\/div>\n \n

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\n \"\" <\/div>\n
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Beeinflusst der Schreibstil die Wirkung wissenschaftlicher Texte?<\/p>\n

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28.06.2021<\/div>\n <\/div>\n

Die Bedeutung und Qualit\u00e4t neuer Forschungsergebnisse in einem wissenschaftlichen Artikel wird oft dadurch gemessen, wie h\u00e4ufig dieser Artikel zitiert …<\/p>\n Mehr erfahren<\/a>\n <\/div>\n<\/div>\n \n

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\n \"\" <\/div>\n
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Force distribution analysis (FDA)<\/p>\n

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30.01.2020<\/div>\n <\/div>\n

Force distribution analysis (FDA) is a method to detect and follow force and stress propagation in proteins, reminiscent of Finite Element …<\/p>\n Mehr erfahren<\/a>\n <\/div>\n<\/div>\n \n

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\n \"\" <\/div>\n
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Mechanical properties of silk<\/p>\n

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18.12.2014<\/div>\n <\/div>\n

Silk is one of the many biomaterials with mechanical properties not yet reached by synthetic counterparts. Silk fibers have an outstanding …<\/p>\n Mehr erfahren<\/a>\n <\/div>\n<\/div>\n \n

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Mechanical properties of Nacre<\/p>\n

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2.12.2014<\/div>\n <\/div>\n

Nacre, also known as mother-of-pearl, is a biocomposite located at the inner layer of seashells, with exceptional mechanical properties such as …<\/p>\n Mehr erfahren<\/a>\n <\/div>\n<\/div>\n \n

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Structure-based Drug design<\/p>\n

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14.11.2014<\/div>\n <\/div>\n

Structure-based design methods have proven effective in every aspect of drug design – from lead discovery, development, through guiding clinical trials. …<\/p>\n Mehr erfahren<\/a>\n <\/div>\n<\/div>\n \n

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\n \"\" <\/div>\n
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Force-driven allostery in proteins<\/p>\n

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11.11.2014<\/div>\n <\/div>\n

Allostery in proteins plays a significant role such as cell signalling or gene and enzyme regulations. Allostery is characterized by a …<\/p>\n Mehr erfahren<\/a>\n <\/div>\n<\/div>\n \n

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\n \"\" <\/div>\n
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Mechano(bio)chemistry<\/p>\n

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30.10.2014<\/div>\n <\/div>\n

Chemical and enzymatic reactions can be guided by mechanical stress. While single molecule force spectroscopy is an emerging technique to study …<\/p>\n Mehr erfahren<\/a>\n <\/div>\n<\/div>\n \n <\/div>\n\n <\/div>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

Aktuelle Projekte Abgeschlossene Projekte<\/p>\n","protected":false},"author":3,"featured_media":40647,"parent":40,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"page-templates\/group.php","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"hits-research-group":[1296],"class_list":["post-1400","page","type-page","status-publish","has-post-thumbnail","hentry","hits-research-group-mbm-de"],"acf":[],"yoast_head":"\nProjekte - HITS gGmbH<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.h-its.org\/de\/forschung\/mbm\/projekte\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Projekte - HITS gGmbH\" \/>\n<meta property=\"og:description\" content=\"Aktuelle Projekte Abgeschlossene Projekte\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.h-its.org\/de\/forschung\/mbm\/projekte\/\" \/>\n<meta property=\"og:site_name\" content=\"HITS gGmbH\" \/>\n<meta property=\"article:modified_time\" content=\"2021-06-22T10:35:46+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.h-its.org\/de\/wp-content\/uploads\/sites\/2\/2019\/12\/MBM.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1340\" \/>\n\t<meta property=\"og:image:height\" content=\"1340\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.h-its.org\/de\/forschung\/mbm\/projekte\/\",\"url\":\"https:\/\/www.h-its.org\/de\/forschung\/mbm\/projekte\/\",\"name\":\"Projekte - 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