{"id":2712,"date":"2014-11-11T16:12:12","date_gmt":"2014-11-11T15:12:12","guid":{"rendered":"http:\/\/www.h-its.org\/?page_id=2712"},"modified":"2022-04-14T10:47:23","modified_gmt":"2022-04-14T08:47:23","slug":"images-movies","status":"publish","type":"page","link":"https:\/\/www.h-its.org\/de\/forschung\/mbm\/images-movies\/","title":{"rendered":"Bilder und Filme"},"content":{"rendered":"\n<h3 class=\"wp-block-heading\">Videos<\/h3>\n\n\n\n<figure class=\"wp-block-video alignleft\"><video controls src=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2021\/06\/1_angle_0_anchor.mp4\"><\/video><figcaption>The movie shows two subdomains of the focal adhesion protein Talin (blue) in search of membrane (grey) interactions. I chose this movie because, even though everything is governed by random motion, the search of the little &#8222;arm&#8220; looks almost animate. Once first contact is made the protein embraces more contact points, ignoring all Covid-regulation. This is probably something we can all relate to. The simulation vividly showcases how the flexibility of a protein structure can be a great advantage for finding interactions.<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-video alignright\"><video controls src=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2021\/06\/3_Contest_movie.mp4\"><\/video><figcaption>Matter, living or non-living, is all around us. Understanding it would be the key to<br>understanding our planet, our lives and ourselves. Polymers are a type of matter or substance<br>consisting of repeating monomers (sub-units), linked together to form extended chains. Due<br>to their wide range of properties, polymers play a crucial and omnipresent role in every aspect<br>of life. In an effort to understand their intrinsic properties, such as the amount of stress a<br>polymer can take before rupturing, we are simulating bulk Polystyrene under a pulling force<br>until breaking. By calculating the force necessary for breaking along with the stress and strain<br>exerted on the polymer we can calculate quantities such as the tensile strength and the<br>toughness of the material.<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-video\"><video controls src=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2021\/06\/6_movie.mp4\"><\/video><figcaption>Integrin-linked Kinase (ILK) and its binding partner parvin, two proteins important for<br>cell attachments, are simulated under mechanical force. Once the interface breaks, mechanical<br>signaling from the extracellular to the intracellular stops.<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-video\"><video controls src=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2021\/06\/7_ig27.mp4\"><\/video><figcaption>Force-induced disulfide bond swapping in a protein domain (More info: K Kolsek, C Aponte-<br>Santamar\u00eda, and F Gr\u00e4ter. Sci. Rep . 7: 9858, 2017).<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-video\"><video controls src=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2021\/06\/8_vwf-a2-disulphide.mp4\"><\/video><figcaption>Change in flexibility of the von Willebrand factor A2 domain upon reduction of the C1669-<br>C1670 disulfide bond (More info: D Butera, et al. Science Adv. 4: eaaq1477, 2018).<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-video\"><video controls src=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2021\/06\/9_vwf-a1a2.mp4\"><\/video><figcaption>Force-induced dissociation of von Willebrand factor A1 and A2 domains (more info: Biophys. J.<br>108: 2312-2321, 2015).<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-video\"><video height=\"2096\" style=\"aspect-ratio: 3840 \/ 2096;\" width=\"3840\" controls src=\"https:\/\/www.h-its.org\/de\/wp-content\/uploads\/sites\/2\/2022\/04\/4_FineToCoarseSmoother.mp4\"><\/video><figcaption>PPEs are a class of conjugated, semi flexible polymers, which self-assemble through alignment<br>as opposed to entanglement, as shown in the video.<br>We apply coarse-grained Molecular Dynamics to reduce the atomistic degrees of freedom and<br>understand the large-scale structural organization of a PPEs.<br>So far, we followed the Martini 3 philosophy to obtain a coarse (orange) respresentation for the<br>fine (black) PPE structure., which enables us to simulate<br>larger PPE bulk systems on longer timescales.<\/figcaption><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\">Stress-induced rupture of a circular graphene sheet<\/h3>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignleft\"><a href=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2014\/10\/g.00014.png\"><img decoding=\"async\" src=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2014\/10\/g.00014-300x225.png\" alt=\"\" class=\"wp-image-3801\" \/><\/a><figcaption>Graphene<\/figcaption><\/figure><\/div>\n\n\n\n<p>The movies show the rupture of a graphene sheet upon indentation by an atomic force microscope tip.<\/p>\n\n\n\n<p>Shown in both cases are&nbsp;a color-coded representation of stress due to indentation. Green represents low levels of background stress due to thermal fluctuations of the graphene atoms; orange represents high stress, delimiting the area in which the bond breaking will very probably take place.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"http:\/\/www.h-its.org\/wp-content\/uploads\/2014\/11\/bluesphere-large-black-1024x199.png\" alt=\"\" class=\"wp-image-3767\" \/><\/figure>\n\n\n\n<p>Rupture seen from the side. <a rel=\"noreferrer noopener\" href=\"http:\/\/www.h-its.org\/wp-content\/uploads\/2014\/12\/breaking_stress_whole1.mpg\" target=\"_blank\">MPG, 11.3 MB, 768\u00d7576 pixel<\/a><\/p>\n\n\n\n<p>Rupture seen from the bottom&nbsp;<a rel=\"noreferrer noopener\" href=\"http:\/\/www.h-its.org\/wp-content\/uploads\/2014\/12\/breaking_pf_detail.mpg\" target=\"_blank\">MPG, 13.1&nbsp;MB, 768\u00d7576 pixel<\/a><br><\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Bilder<\/h2>\n\n\n\n<figure class=\"wp-block-gallery columns-5 is-cropped wp-block-gallery-1 is-layout-flex wp-block-gallery-is-layout-flex\"><ul class=\"blocks-gallery-grid\"><li class=\"blocks-gallery-item\"><figure><a href=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2014\/11\/allAtomAragonite.png\"><img decoding=\"async\" src=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2014\/11\/allAtomAragonite.png\" alt=\"\" data-id=\"4024\" class=\"wp-image-4024\" \/><\/a><\/figure><\/li><li class=\"blocks-gallery-item\"><figure><a href=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2014\/11\/crysPS.png\"><img decoding=\"async\" src=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2014\/11\/crysPS.png\" alt=\"\" data-id=\"4022\" class=\"wp-image-4022\" \/><\/a><\/figure><\/li><li class=\"blocks-gallery-item\"><figure><a href=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2014\/12\/meltedPS.png\"><img decoding=\"async\" src=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2014\/12\/meltedPS.png\" alt=\"\" data-id=\"4020\" class=\"wp-image-4020\" \/><\/a><\/figure><\/li><li class=\"blocks-gallery-item\"><figure><a href=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2014\/11\/FigureAnnRepHITS.png\"><img decoding=\"async\" src=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2014\/11\/FigureAnnRepHITS.png\" alt=\"\" data-id=\"3885\" class=\"wp-image-3885\" \/><\/a><\/figure><\/li><li class=\"blocks-gallery-item\"><figure><a href=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2014\/10\/g.00014.png\"><img decoding=\"async\" src=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2014\/10\/g.00014.png\" alt=\"\" data-id=\"3801\" class=\"wp-image-3801\" \/><\/a><\/figure><\/li><li class=\"blocks-gallery-item\"><figure><a href=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2014\/11\/ck-vwf-page.png\"><img decoding=\"async\" src=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2014\/11\/ck-vwf-page.png\" alt=\"\" data-id=\"3592\" class=\"wp-image-3592\" \/><\/a><\/figure><\/li><li class=\"blocks-gallery-item\"><figure><a href=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2014\/10\/masterpiece.png\"><img decoding=\"async\" src=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2014\/10\/masterpiece.png\" alt=\"\" data-id=\"3370\" class=\"wp-image-3370\" \/><\/a><\/figure><\/li><li class=\"blocks-gallery-item\"><figure><a href=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2014\/10\/TF.png\"><img decoding=\"async\" src=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2014\/10\/TF.png\" alt=\"\" data-id=\"3368\" class=\"wp-image-3368\" \/><\/a><\/figure><\/li><li class=\"blocks-gallery-item\"><figure><a href=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2014\/11\/ESH_Graphics.png\"><img decoding=\"async\" src=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2014\/11\/ESH_Graphics.png\" alt=\"\" data-id=\"2836\" class=\"wp-image-2836\" \/><\/a><\/figure><\/li><li class=\"blocks-gallery-item\"><figure><a href=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2014\/11\/Bogdan_graphene_news1.png\"><img decoding=\"async\" src=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2014\/11\/Bogdan_graphene_news1.png\" alt=\"\" data-id=\"2724\" class=\"wp-image-2724\" \/><\/a><\/figure><\/li><li class=\"blocks-gallery-item\"><figure><a href=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2014\/11\/illustration.png\"><img decoding=\"async\" src=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2014\/11\/illustration.png\" alt=\"\" data-id=\"2736\" class=\"wp-image-2736\" \/><\/a><\/figure><\/li><li class=\"blocks-gallery-item\"><figure><a href=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2014\/11\/Fig4.png\"><img decoding=\"async\" src=\"https:\/\/www.h-its.org\/wp-content\/uploads\/2014\/11\/Fig4.png\" alt=\"\" data-id=\"9335\" class=\"wp-image-9335\" \/><\/a><\/figure><\/li><\/ul><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Videos Stress-induced rupture of a circular graphene sheet The movies show the rupture of a graphene sheet upon indentation by an &#8230;<\/p>\n","protected":false},"author":3,"featured_media":40647,"parent":40,"menu_order":7,"comment_status":"closed","ping_status":"closed","template":"page-templates\/group.php","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"hits-research-group":[1296],"class_list":["post-2712","page","type-page","status-publish","has-post-thumbnail","hentry","hits-research-group-mbm-de"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Bilder und Filme - HITS gGmbH<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.h-its.org\/de\/forschung\/mbm\/images-movies\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Bilder und Filme - HITS gGmbH\" \/>\n<meta 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