Auriga Project

The Auriga Project is a large suite of high-resolution magneto-hydrodynamical simulations of Milky Way-sized galaxies, simulated in a fully cosmological environment by means of the ‘zoom-in’ technique. It is simulated with our state-of-the-art hydrodynamic moving mesh code AREPO, and includes a comprehensive galaxy formation model based on the successful cosmological simulation Illustris. We have setup…

New TRAPP webserver for studying TRAnsient Pockets in Proteins

Many drugs exert their therapeutic effects by binding in cavities or pockets on specific target protein macromolecules. The binding pockets on proteins are mobile and dynamic and constantly changing shape. Some pockets or subpockets can be described as transient because they are not always present in the given protein. In structure-based drug design procedures, the…