A team of researchers led by scientists in Vienna, Dresden and Heidelberg has decoded the entire genetic information of the Mexican salamander axolotl. The axolotl genome, which is the largest genome ever to be sequenced, will be a powerful tool to study the molecular basis for re-growing limbs and other forms of regeneration. The journal NATURE publishes the news in its current issue.
The planarian flatworm Schmidtea mediterranea is an extraordinary animal. Even when cut into tiny pieces, each piece can regenerate back into a complete and perfectly proportioned miniature planarian. Key to this ability are fascinating adult stem cells, a single one of which can restore a complete worm. But how Schmidtea mediterranea achieves these feats is so far poorly understood. An important step towards this goal is the first highly contiguous genome assembly of Schmidtea mediterranea that researchers at the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) in Dresden in cooperation with the Heidelberg Institute for Theoretical Studies (HITS) report in the current issue of Nature.