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DTSTART;TZID=Europe/Berlin:20230123T110000
DTEND;TZID=Europe/Berlin:20230123T120000
DTSTAMP:20260409T131010
CREATED:20230111T130228Z
LAST-MODIFIED:20230116T123339Z
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SUMMARY:Colloquium Peter Smillie: Counting fullerenes with modular forms — an application of number theory to carbon chemistry
DESCRIPTION:By Peter Smillie\, Mathematical Institute\, Heidelberg University \nFullerenes are polyhedral molecules made of carbon atoms\, first discovered in 1985. A few isomers are naturally occurring and many more have since been synthesised\, with numerous applications across materials science\, biology\, and medicine. One source of theoretical interest in fullerenes is that there are a lot of them; it is well known that if n is large\, you can synthesise about n^9 (n to the 9th power) distinct isomers with exactly n carbon atoms. \nAs I will explain\, the set of all isomers has a beautiful mathematical structure\, corresponding to certain integral points in 18 dimensional space. A fundamental problem is to predict the chemical properties of an isomer from this mathematical description. This is the goal of a joint project with Ganna Gryn’ova at HITS. \nI will present a surprising result\, joint with Philip Engel\, that there exists an exact formula for the number of distinct isomers with n atoms using modular forms\, which are certain sequences with deep connections to the prime numbers. We are still working out the details\, but this should reproduce tables that mathematical chemists have computed up to n= 300 or so\, and let us calculate essentially instantaneously the number of isomers for any n. \n  \nShort CV: \nPeter Smillie is a “Geometry Plus” Junior Professor at the University of Heidelberg. His primary research is in differential geometry\, especially the study of minimal surfaces in symmetric spaces and moduli spaces of geometric structures. It was his work on the moduli space of polyhedra that led to his discovery with P. Engel in 2017 of the connection between polyhedra and modular forms. In ongoing joint work with F. \nBonsante and A. Seppi\, he is developing new tools to study the asymptotic behavior of special surfaces in spacetime. In 2022\, together with N. Sagman\, he found a counterexample to the well-known Labourie conjecture in higher Teichmüller theory. He received his Ph.D. in mathematics from Harvard in 2018\, and held post-doctoral positions at the IHES in Paris and at Caltech\, before starting at Heidelberg in 2022. \n  \nREGISTRATION: \nThe talk will be hybrid.\nIf you would like to participate in person\, please register in advance at benedicta.frech@h-its.org.\nIf you would like to participate online\, please register in advance here: https://kta-email.zoom.us/meeting/register/tJYqf-Ctrz0vHNcjyGBh6Px8jdpz8HulIYJx.\n\n\n\nAfter registering\, you will receive a confirmation email containing information about joining the meeting.\n\n\nIn case you are not able to attend\, you can watch the talk afterwards on the HITS YouTube channel: https://www.youtube.com/user/TheHITSters.
URL:https://www.h-its.org/event/colloquium-peter-smillie/
LOCATION:Studio Villa Bosch\, Schloss-Wolfsbrunnenweg 33\, Heidelberg\, 69118\, Germany
CATEGORIES:Colloquia,Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2023/01/Foto_Smillie.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20221121T110000
DTEND;TZID=Europe/Berlin:20221121T120000
DTSTAMP:20260409T131010
CREATED:20221027T120742Z
LAST-MODIFIED:20221103T121556Z
UID:65159-1669028400-1669032000@www.h-its.org
SUMMARY:HITS-SIMPLAIX joint colloquium Michele Ceriotti: Atomic-scale modeling in the age of machine learning
DESCRIPTION:By Michele Ceriotti\, EPFL STI SMX-GE\, Lausanne\, Switzerland \nWhen modeling materials and molecules at the atomic scale\, achieving a realistic level of complexity and making quantitative predictions are usually conflicting goals.\nData-driven techniques have made great strides towards enabling simulations of materials in realistic conditions with uncompromising accuracy.\nIn this talk I will summarize the core concepts that have driven the extraordinarily fast progress of the field\, discussing the relationship to more general concepts in geometric machine learning.\nI will describe some of the most promising modeling techniques that combine physics-inspired and data-driven paradigms\, indicate the most pressing open challenges\, and present several compelling examples ranging from water to semiconductors and from metals to molecular materials. \n  \nShort CV: \nMichele Ceriotti received his Ph.D. in Physics from ETH Zürich. He spent three years in Oxford as a Junior Research Fellow at Merton College. Since 2013 he leads the laboratory for Computational Science and Modeling\, in the institute of Materials at EPFL\, that focuses on method development for atomistic materials modeling based on statistical mechanics and machine learning. He is one of the core developers of several open-source software packages\, including http://ipi-code.org and http://chemiscope.org\, and proudly serves the atomistic modeling community as an associate editor of the Journal of Chemical Physics\, as a moderator of the physics.chem-ph section of the arXiv\, and as an editorial board member of Physical Review Materials. \n  \nREGISTRATION: \nThe talk will be hybrid.\nIf you would like to participate in person\, please register in advance at benedicta.frech@h-its.org.\nIf you would like to participate online\, please register in advance here:\nhttps://kta-email.zoom.us/meeting/register/tJElcu6sqDktHdDUmD6C08q__YImcdMaYdAE\n\nAfter registering\, you will receive a confirmation email containing information about joining the meeting.\n\n\n\n\n\n\nIn case you are not able to attend\, you can watch the talk afterwards on the HITS YouTube channel: https://www.youtube.com/user/TheHITSters.
URL:https://www.h-its.org/event/hits-simplaix-joint-colloquium-michele-ceriotti/
LOCATION:Studio Villa Bosch\, Schloss-Wolfsbrunnenweg 33\, Heidelberg\, 69118\, Germany
CATEGORIES:Colloquia,Public Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20221024T110000
DTEND;TZID=Europe/Berlin:20221024T120000
DTSTAMP:20260409T131010
CREATED:20220926T102613Z
LAST-MODIFIED:20220926T102956Z
UID:64462-1666609200-1666612800@www.h-its.org
SUMMARY:Colloquium David Dao: Gainforest: Using artificial intelligence to help restore the natural world
DESCRIPTION:By David Dao\, GainForest/PhD candidate ETH Zurich\, Switzerland \nNature has been deteriorating at rates unparalleled in human history and the implications are global. Climate change and biodiversity loss are two bullets in the same gun. Perils we face in parallel\, both driven by deforestation and land use change. If global tropical deforestation were a country\, its resulting emissions would be larger than the whole of the European Union. Time is running out and we need urgent climate and environmental action.\nUnfortunately\, we cannot value what we cannot measure. And we are failing to capture nature’s full contributions to society. In this talk\, we argue that machine learning (ML) can play a significant role in responding to this critical call for action – but only when we develop ML algorithms in co-design with local and Indigenous communities – by empowering digital monitoring\, reporting and verification and conservation projects. \nWe will present our work at Gainforest\, a global science-based non-profit and currently a semi-finalist of the $10M XPRIZE Rainforest\, and how Gainforest is deploying affordable top-down and bottom-up monitoring solutions on the ground in partnership with the government of Paraguay and conservation partners in the Global South. Lastly\, we will discuss how increased transparency and decentralized science for nature can enable novel financial schemes to tackle global deforestation. \n  \nShort CV: \nDavid Dao (he/him) is the founder of GainForest and an Artificial Intelligence (AI) researcher at ETH Zurich. GainForest is a non-profit grantee of Microsoft’s AI for Earth program and Filecoin Green\, and a $10M XPRIZE Rainforest Semi-Finalist to prevent deforestation. In co-design with local communities in South America and Southeast Asia\, GainForest develops a global assessment protocol that rewards sustainable nature stewardship and has been featured by BBC Radio4\, World Economic Forum\, Microsoft\, Handelsblatt\, Boston Consulting Group\, and the United Nations. At ETH Zurich\, David founded the Climate + AI initiative at DS3Lab and maintains Github’s most starred collection on ethical use of AI (“Awful AI”). In close collaboration with the World Wildlife Fund (WWF)\, MIT\, and Restor they develop satellite-based monitoring algorithms to assess biodiversity. Additionally\, he leads the joint Kara Data Marketplace initiative with Stanford\, UC Berkeley\, and Oasis Labs. David’s research won best papers and several academic grants. Previously\, he was an engineer in Silicon Valley and a research fellow at Berkeley AI Research (BAIR)\, Stanford University\, and Broad Institute of MIT and Harvard. David is a Global Shaper at World Economic Forum\, the Forest Lead of Climate Change AI\, a Climate Leader at Climate Reality Project\, a UN youth delegate for UN since COP23\, an advisor to the UNFCCC Resilience Frontiers and Paraguay’s official COP delegation\, and a mentor at Creative Destruction Lab Paris. In his spare time\, David explores tropical rainforests in South America and the deep sea of Southeast Asia. \n  \nREGISTRATION: \nThe talk will be hybrid.\nIf you would like to participate in person\, please register in advance at benedicta.frech@h-its.org.\nIf you would like to participate online\, please register in advance here: https://kta-email.zoom.us/meeting/register/tJMrfu6spzIuHtOgC6naQ96p1gN2L58Lcev9\n\n\n\nAfter registering\, you will receive a confirmation email containing information about joining the meeting.\n\n\nIn case you are not able to attend\, you can watch the talk afterwards on the HITS YouTube channel: https://www.youtube.com/user/TheHITSters.
URL:https://www.h-its.org/event/colloquium-david-dao/
CATEGORIES:Colloquia,Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2022/09/Foto-David.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20221004T110000
DTEND;TZID=Europe/Berlin:20221004T120000
DTSTAMP:20260409T131010
CREATED:20220804T083033Z
LAST-MODIFIED:20220825T113442Z
UID:63588-1664881200-1664884800@www.h-its.org
SUMMARY:Colloquium Sarbani Basu: Learning physics through astronomy - the Sun and Stars as laboratories
DESCRIPTION:By Sarbani Basu\, Department of Astronomy\, Yale University\, USA \nWe normally rely on physics to interpret and understand astrophysical processes. However\, with precise seismic data from the Sun and other stars\, we can use astrophysics to inform us about the physical properties of stellar matter\, and in some cases inform us even about fundamental physics. \nIn this talk I shall describe how we use seismic data to study properties of matter. I shall also touch up how solar and stellar data have been used to put constraints on fundamental physics\, such as the time variation of the gravitational constant. \n  \nShort CV: \nSarbani Basu is the William K. Lanman Jr. Professor of Astronomy at Yale University\, USA. \nProf. Basu was educated in India. She obtained her Ph.D. in 1993 from the University of Mumbai for work done at the Tata Institute of Fundamental Research. Subsequently\, she did her postdoctoral work in helioseismology. She was a post-doc at the Queen Mary & Westfield College\, London\, and University of Aarhus\, Denmark before moving to the US in 1997 to join the Institute for Advanced Study\, Princeton.  She joined Yale University in 2000. She chaired the Department of Astronomy from 2016-2022. \nProf. Basu conducts research in the fields of solar and stellar astrophysics using seismic data. She has been studying both the general properties and the details of the structure and dynamics of the Sun\, focusing on solar-cycle dependences. Her interest in putting the Sun in a general astronomical context has led her to use asteroseismic data obtained by the Kepler and TESS spacecrafts to study other stars.  She has published over 290 peer-reviewed articles and a full-length book. Her work has garnered more than 25\,000 citations. Her papers can be found linked to her website at http://campuspress.yale.edu/sarbanibasu/ \nProf. Basu has won several awards and accolades. She received the Vainu Bappu Gold Medal of the Astronomical Society of India in 1996 for her early work on helioseismology.  In 2018\, she was awarded the George Ellery Hale award of the Solar Physics Division of the American Astronomical Society for her contributions to the understanding of the internal structure and dynamics of the Sun and stars. Her other achievements include the US National Science Foundation’s CAREER award in 2004\, being elected as a Fellow of the American Association for the Advancement of Science in 2015 and being elected to be among the inaugural batch of Fellows of the American Astronomical Society in 2020. \n  \nREGISTRATION: \nThe talk will be hybrid.\nIf you would like to participate in person\, please register in advance at benedicta.frech@h-its.org.\nIf you would like to participate online\, please register in advance here: https://kta-email.zoom.us/meeting/register/tJ0kceqoqzopH9N8g5xeY6Cs28iVZ7m1ga-g\n\n\n\nAfter registering\, you will receive a confirmation email containing information about joining the meeting.\n\n\nIn case you are not able to attend\, you can watch the talk afterwards on the HITS YouTube channel: https://www.youtube.com/user/TheHITSters.\n 
URL:https://www.h-its.org/event/sarbani-basu/
CATEGORIES:Colloquia,Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2022/08/Photo.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20220718T110000
DTEND;TZID=Europe/Berlin:20220718T120000
DTSTAMP:20260409T131010
CREATED:20220705T112852Z
LAST-MODIFIED:20220705T123802Z
UID:63083-1658142000-1658145600@www.h-its.org
SUMMARY:Eike Hermann Müller: Efficient fast multipole methods for (kinetic) Monte Carlo simulations of interacting particle systems
DESCRIPTION:By Eike Hermann Müller\, Department of Mathematical Sciences\, University of Bath\, UK \nIncluding electrostatics in (kinetic) Monte Carlo simulations of interacting particles is challenging due to the long-range nature of the Coulomb potential. As a result\, the computational complexity grows rapidly with N\, the number of particles in the system. While the Fast Multipole Method (FMM) allows the computation of electrostatic interactions for a fixed configuration in O(N) time\, a full sweep over all particles in a (kinetic) Monte Carlo update is still too expensive if FMM is applied naively. To overcome this issue\, we developed modified versions of FMM which require only O(1) computations per particle hop in kinetic Monte Carlo or O(log(N)) operations for a single-particle move in standard Monte Carlo. The algorithms are implemented in a new performance portable Python framework for molecular simulations. Our framework provides an abstraction for typical operations such as loops over all particle pairs\, which are orchestrated by control flow in Python. While this allows the easy implementation of simulation algorithms in a high-level language\, under the hood code generation guarantees the efficient execution on different parallel computer architectures. \n  \nShort CV: \nEike Mueller is an Associate Professor (Senior Lecturer) for Scientific Computing in the Department of Mathematical Sciences at the University of Bath (UK). Originally trained as a physicist\, Eike has worked on the development and implementation of efficient numerical algorithms to tackle challenging problems in science and engineering. His work on new multigrid solvers for partial differential equations in atmospheric fluid dynamics has led to significant impact by improving the performance of the UK’s operational climate- and weather forecast model. More generally\, Eike’s research focuses on the development of fast\, parallel algorithms in interdisciplinary contexts. While collaborating with meteorologists\, chemists and physicists\, Eike has worked on the application of multilevel methods to predict the spread of atmospheric pollutants\, to simulate path integrals in quantum mechanics and to accelerate (kinetic) Monte Carlo simulations. In addition to the design of new numerical methods\, Eike is also interested in their efficient implementation\, performance portability and sustainable software engineering.\nBefore joining the University of Bath as a PostDoc in 2011\, Eike completed a PhD in computational particle physics in Edinburgh (2009) and worked as a scientist at the UK Meteorological Office (2009-2011). https://people.bath.ac.uk/em459/ \n  \nREGISTRATION: \nThe talk will be hybrid.\nIf you would like to participate in person\, please register in advance at benedicta.frech@h-its.org.\nIf you would like to participate online\, please register in advance here: https://kta-email.zoom.us/meeting/register/tJUodO2hrTIuHdPIM5No5L88WVkpvkXbTVhM.\n\n\nAfter registering\, you will receive a confirmation email containing information about joining the meeting.\n\n\nIn case you are not able to attend\, you can watch the talk afterwards on the HITS YouTube channel: https://www.youtube.com/user/TheHITSters.\n 
URL:https://www.h-its.org/event/eike-hermann-mueller/
CATEGORIES:Colloquia,Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2022/06/Foto_Eike-Müller.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20220709T110000
DTEND;TZID=Europe/Berlin:20220709T170000
DTSTAMP:20260409T131010
CREATED:20220629T130711Z
LAST-MODIFIED:20220629T130711Z
UID:62981-1657364400-1657386000@www.h-its.org
SUMMARY:Open Day at HITS
DESCRIPTION:Come and join us for our Open Day at HITS on Saturday\, 9 July\, from 11am-5pm \n\n\n\nAfter four years the Heidelberg Institute for Theoretical Studies will open its doors to the public again. Under the overall theme of “Digital Worlds 20.22” the program includes science talks in English and German\, presentations and hands-on stations\, all showcasing the research of the Institute. \nOne of the highlights this year will be the guided tours – also in English and German – through the HITS garden. \nA free shuttle bus will run from 11am to 5.30pm every 30 minutes between S-Bahnhof Altstadt (Karlstor) and HITS\, free parking is available in the car park “Unter der Boschwiese”. Refreshments will be served throughout the day.
URL:https://www.h-its.org/event/open-day-at-hits/
CATEGORIES:Public Events
ATTACH;FMTTYPE=image/png:https://www.h-its.org/wp-content/uploads/2022/06/HITS_TdoT_20.22_Plakat.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20220706T110000
DTEND;TZID=Europe/Berlin:20220706T120000
DTSTAMP:20260409T131010
CREATED:20220620T111829Z
LAST-MODIFIED:20260126T105139Z
UID:62718-1657105200-1657108800@www.h-its.org
SUMMARY:Antonis Rokas: Incongruence in the Tree of Life
DESCRIPTION:By Antonis Rokas\, Department of Biological Sciences\, Vanderbilt University\, USA \nThe use of genome-scale amounts of data and sophisticated statistical phylogenetic approaches have greatly aided the reconstruction of a broad sketch of the tree of life and resolved many of its branches. However\, incongruence—the inference of conflicting evolutionary histories stemming from a multitude of analytical and biological factors—remains pervasive\, especially for certain key branches in life’s history. In my talk\, I will discuss the factors that drive incongruence; methodological advances to diagnose and handle incongruence; and important avenues for future research. Detecting and understanding the causes of incongruence in phylogenomic data sets is essential for understanding the process of phylogenesis and for the accurate reconstruction and interpretation of the tree of life. \n  \n  \nREGISTRATION: \nThe talk will be hybrid.\nIf you would like to participate in person\, please register in advance at benedicta.frech@h-its.org.\nIf you would like to participate online\, please register in advance here: https://kta-email.zoom.us/meeting/register/tJIucOqprz0sGdLrk5z-hO1PMAox4hA0mF-M\n\n\nAfter registering\, you will receive a confirmation email containing information about joining the meeting.\n\n\nIn case you are not able to attend\, you can watch the talk afterwards on the HITS YouTube channel: https://www.youtube.com/user/TheHITSters.\n 
URL:https://www.h-its.org/event/antonis-rokas/
CATEGORIES:Colloquia,Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2022/06/Foto_Antonis-Rokas.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20220628T110000
DTEND;TZID=Europe/Berlin:20220628T120000
DTSTAMP:20260409T131010
CREATED:20220601T121821Z
LAST-MODIFIED:20220602T082942Z
UID:62234-1656414000-1656417600@www.h-its.org
SUMMARY:Julio Saez-Rodriguez: Computational models from multi-omics data for personalized medicine
DESCRIPTION:By Julio Saez-Rodriguez\, Heidelberg University Hospital\, Institute of Computational Biomedicine \nModern technologies allow us to profile in high detail biological and medical samples at fast decreasing costs. New technologies are opening new data modalities\, including to measure at the single-cell level and with spatial resolution.  Computational models\, in particular those built with machine learning\, are expected to help us to extract insight form these data.  Using biological knowledge to aid machine learning can significantly improve the results. Towards this end\, we have developed a number of tools that range from a meta-resource of biological knowledge to methods to infer pathway and transcription factor activities from gene expression and subsequently infer causal paths among them. Furthermore\, we have developed approaches to build dynamic logic models of molecular networks and how they response to perturbations such as drug treatment. I will illustrate their utility in cases of biomedical relevance and show how they  improve our understanding of molecular processes\, identify biomarkers\, and point at  novel therapeutic opportunities. \nShort CV \nJulio Saez-Rodriguez is Professor of Medical Bioinformatics and Data Analysis at the Faculty of Medicine of Heidelberg University\, director of the Institute for Computational Biomedicine\, group leader of the EMBL-Heidelberg University Molecular Medicine Partnership Unit\, a member of the Heidelberg ELLIS Unit\, and a co-director of the DREAM challenges. He holds a PhD (2007) in Chemical Engineering. He was a postdoctoral fellow at Harvard Medical School and M.I.T (2007- 2010)\, group leader at EMBL-EBI\, Cambridge (2010-2015)\, and professor of Computational Biomedicine at RWTH Aachen (2015-2018).  He is interested in developing and applying computational methods to acquire a functional understanding of signaling networks and their deregulation in disease\, and to apply this knowledge to develop novel therapeutics. Current emphasis in his group is on use of single-cell technologies\, multi-omics integration\, and understanding multi-cellular communication. While his previous focus has been on cancer\, he is increasingly working on autoimmune\, kidney and cardiovascular disease. More information at www.saezlab.org. \n  \nREGISTRATION: \nThe talk will be hybrid.\nIf you would like to participate in person\, please register in advance at benedicta.frech@h-its.org.\nIf you would like to participate online\, please register in advance here: https://kta-email.zoom.us/meeting/register/tJIvce-grD0rHtEOfOHnabJJ3qeTO4LDogAf\n\n\nAfter registering\, you will receive a confirmation email containing information about joining the meeting.\n\n\nIn case you are not able to attend\, you can watch the talk afterwards on the HITS YouTube channel: https://www.youtube.com/user/TheHITSters.\n 
URL:https://www.h-its.org/event/julio-saez-rodriguez/
CATEGORIES:Colloquia,Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2022/06/FotoJulio_2017.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20220524T160000
DTEND;TZID=Europe/Berlin:20220524T170000
DTSTAMP:20260409T131010
CREATED:20220503T103555Z
LAST-MODIFIED:20220504T090214Z
UID:61762-1653408000-1653411600@www.h-its.org
SUMMARY:Carl Smith: 'Fortress Australia' and 'E-Narnia': did unique societal adaptations help Australia and Estonia during the pandemic?
DESCRIPTION:By Carl Smith \nIn late 2021\, Australian science journalist Carl Smith was granted a rare and special privilege: he was allowed to leave his country. \nFor most people living in Australia at the time\, this was not possible – because it was one of the few nations that continued to aim for ‘covid zero’. This meant closing borders\, tracing every contact\, stamping out every infection cluster\, and multiple rounds of lockdowns. \nAfter arriving in Europe in early 2022\, he visited another country on the other side of the world that had a very different but equally unique experience of the pandemic. \nThe small Baltic nation of Estonia is one of the most advanced ‘digital societies’ in the world. Sophisticated digital infrastructure created before the pandemic limits the need for Estonians to leave their homes to interact with their government or local companies. \nSo\, what impacts did these unusual factors have on each country during the rampage of the Sars-CoV-2 virus? \nAs we continue to hear stories of how other nations battled the COVID-19 pandemic\, how do we even define ‘success’? And what can we learn from countries like Australia and Estonia as societies step into a ‘new normal’? \n  \nCarl Smith is a science journalist\, broadcaster & podcaster working for the Australian Broadcasting Corporation (ABC)’s Science Unit. He’s won some of Australia’s most prestigious awards\, including a Walkley Award and the Eureka Prize for Science Journalism. Carl is currently the ‘Journalist in Residence’ at HITS. More about Carl Smith  https://www.carlsmith.co/ \n  \nREGISTRATION: \nThe talk will be hybrid\, with a limited amount of participants on-site.\nIf you would like to participate in person\, please register in advance at benedicta.frech@h-its.org.\nIf you would like to participate online\, please register in advance here: https://kta-email.zoom.us/meeting/register/tJAvf-ivqzksGN33NJrJhv0HRrvdvUuxZnAv.\n\n\nAfter registering\, you will receive a confirmation email containing information about joining the meeting.\n\n\nIn case you are not able to attend\, you can watch the talk afterwards on the HITS YouTube channel: https://www.youtube.com/user/TheHITSters.
URL:https://www.h-its.org/event/public-talk-carl-smith/
CATEGORIES:Colloquia,Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2022/05/Carl_Smith_HF_DSC03153a-1-scaled-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20220516T110000
DTEND;TZID=Europe/Berlin:20220516T120000
DTSTAMP:20260409T131010
CREATED:20220412T101956Z
LAST-MODIFIED:20220413T082358Z
UID:61395-1652698800-1652702400@www.h-its.org
SUMMARY:Colloquium Andreas Reuter: Habitual Inclination Towards Scrutiny: A Brief Reflection on How HITS Came About
DESCRIPTION:By Andreas Reuter \nInstitutes can be created/established for various reasons. Universities (in Germany) do it routinely as a means of structuring their organization. Beauty parlors and private schools like to polish their image by trading under the name of „Institute of XYZ“. And then there are (a few) independent institutes that were established with a more or less specific mission. Those mission statements typically avoid mentioning the expectation underlying the effort in the first place: Be excellent\, win awards. This becomes apparent when analyzing which role models are quoted for the newly established institutes. \nWhether or not such an institute lives up to the aspirations of its founders is often hard to judge. And in fact\, one typically finds that the rationale for setting up the organization is continuously retrofitted to match the actual development. \nHITS was established in 2010\, the discussions about the idea and its implementation having started some three years before. Unfortunately\, not all the people directly involved in defining both structure and mission of the new institute are still around\, but while some of them are\, it probably is interesting to reflect on how the whole thing started and how it evolved – compared to the original expectations. I will give an account of that process\, which (at least initially) was guided by a very simple\, yet ambitious\, recipe formulated by James Bryant Conant: „There is only one proved method of assisting the advancement of pure science: that of picking [individuals] of genius\, backing them heavily\, and leaving them to direct themselves.“ \n  \nREGISTRATION: \nThe colloquium is taking place via Zoom.\nPlease register in advance for this meeting: https://kta-email.zoom.us/meeting/register/tJMkd-ugqTotHdPGt88HGzv33pyb22B8KrJO\n\nAfter registering\, you will receive a confirmation email containing information about joining the meeting.\n\n\nIn case you are not able to attend\, you can watch the talk afterwards on the HITS YouTube channel: https://www.youtube.com/user/TheHITSters.
URL:https://www.h-its.org/event/colloquium-andreas-reuter/
LOCATION:Online
CATEGORIES:Colloquia,Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2022/04/Foto-Reuter-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20220425T160000
DTEND;TZID=Europe/Berlin:20220425T170000
DTSTAMP:20260409T131010
CREATED:20220316T103014Z
LAST-MODIFIED:20260126T095837Z
UID:60964-1650902400-1650906000@www.h-its.org
SUMMARY:Colloquium Ruth Nussinov: Unraveling Oncogenic Mechanisms and their Linkage to Neurodevelopmental Disorders
DESCRIPTION:  \nBy Ruth Nussinov\, National Cancer Institute\, Center for Cancer Research\, USA \nOver the last few years our work has aimed to reveal oncogenic mechanisms of key oncogenic proteins in the Ras signaling network\, including Ras\, Raf\, PI3K\, PTEN\, and more. We aim to understand their activation mechanisms\, mutations\, and signaling. During the last year we have extended our work\, asking how same-gene mutations can drive both cancer and neurodevelopmental disorders. This question has been puzzling. It has also been puzzling why those with neurodevelopmental disorders have a high risk of cancer. Ras\, MEK\, PI3K\, PTEN\, and SHP2 are among the oncogenic proteins that can harbor mutations that encode diseases other than cancer. My talk will describe these\, and the linkage between cancer and neurodevelopmental disorders at the molecular and cellular levels. \n  \n  \nREGISTRATION: \nThe colloquium is taking place via Zoom.\nPlease register in advance for this meeting: https://kta-email.zoom.us/meeting/register/tJUlceCqrDooGtbE0bWgBUhxsI1dtS34VrRJ\n\nAfter registering\, you will receive a confirmation email containing information about joining the meeting.\n\n\nIn case you are not able to attend\, you can watch the talk afterwards on the HITS YouTube channel: https://www.youtube.com/user/TheHITSters.
URL:https://www.h-its.org/event/colloquium-ruth-nussinov/
LOCATION:Online
CATEGORIES:Colloquia,Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2022/03/Foto-Nussinov.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20220221T110000
DTEND;TZID=Europe/Berlin:20220221T120000
DTSTAMP:20260409T131010
CREATED:20220202T101851Z
LAST-MODIFIED:20260126T095847Z
UID:60241-1645441200-1645444800@www.h-its.org
SUMMARY:HITS-SIMPLAIX joint colloquium Frank Noé: Deep Learning for Molecular Physics and Chemistry
DESCRIPTION:By Frank Noé\, Freie Universität Berlin\, Fachbereich Mathematik und Informatik \nAI\, and specifically deep ML methods have a profound impact on industry and information technology. But since recently AI methods are also changing the way we do science. In this talk I will present some of our recent efforts to build machine learning methods that attack fundamental problems in physical and chemical sciences: the sampling problem in physical many-body systems\, and the solution of the quantum-chemical electronic Schrödinger equation. Key in making progress in these hard problems with ML is to interrogate the physical system about what the learning problem should be\, and to encode physical structures\, such as symmetries and conservation laws\, into the ML model. \n  \n  \nREGISTRATION: \nThe colloquium is taking place via Zoom.\nPlease register in advance for this meeting: https://kta-email.zoom.us/meeting/register/tJ0lduutrzkrH9SzLBrAxFA_e3VI2377Ttdq\nAfter registering\, you will receive a confirmation email containing information about joining the meeting.\n\n\nIn case you are not able to attend\, you can watch the talk afterwards on the HITS YouTube channel: https://www.youtube.com/user/TheHITSters.
URL:https://www.h-its.org/event/hits-simplaix-joint-colloquium-frank-noe/
LOCATION:Online
CATEGORIES:Colloquia,Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2022/02/Foto-Noé.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20220124T110000
DTEND;TZID=Europe/Berlin:20220124T110000
DTSTAMP:20260409T131010
CREATED:20220110T094119Z
LAST-MODIFIED:20220110T095919Z
UID:59866-1643022000-1643022000@www.h-its.org
SUMMARY:Colloquium Eva Wolfangel: Immersive Media for Science Journalism and Science Communication
DESCRIPTION:  \nBy Eva Wolfangel\, Journalist\, Speaker\, Moderator \nImmersive Media like Virtual Reality and Augmented Reality offer great possibilities for science communication and science journalism. But nevertheless journalists and communicators often fail to use this new technologies creatively and in to take advantage of the possibilities they offer. In this talk we will discover some amazing best practice experiences and discuss their pros and cons. By analyzing some of the latest VR and AR storytelling projects and experiences we figure out for which communication purposes these new technologies are suitable and what points to consider in order to make meaningful use of the technology. \n  \nCurriculum vitae: \nEva Wolfangel is an award-winning freelance science and tech journalist\, a storyteller and feature writer\, a speaker and moderator. Her focus is on science reporting as well as future technologies\, tech ethics\, cyber security\, virtual reality and neuroscience. She writes for major magazines and newspapers in Germany and Switzerland — including ZEIT\, Geo\, Spiegel\, and NZZ — and produces radio features. As VR Reporterin\, she reports from virtual worlds as part of the journalistic cooperative RiffReporter. Eva’s specialty is to combine creative writing and complex topics in order to reach a broad audience. Eva Wolfangel is part of the class of 2020 of the Knight Science Journalism Fellowship at MIT in Boston. 2020 she was awarded with the German Reporterpreis for her reportage about living in virtual worlds as well as with the Georg von Holtzbrinck Award for Science Journalism. 2018 she was named European Science Journalist of the Year by the Association of British Science Writers. \n  \nREGISTRATION: \nThe colloquium is taking place via Zoom.\nPlease register in advance for this meeting: https://kta-email.zoom.us/meeting/register/tJwtduGhrjgrGtM9817s79kszmunUZ8x_0o0\nAfter registering\, you will receive a confirmation email containing information about joining the meeting.\n\n\nIn case you are not able to attend\, you can watch the talk afterwards on the HITS YouTube channel: https://www.youtube.com/user/TheHITSters.\n 
URL:https://www.h-its.org/event/colloquium-eva-wolfangel/
CATEGORIES:Colloquia,Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2022/01/Foto-Eva-1-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20211122T110000
DTEND;TZID=Europe/Berlin:20211122T120000
DTSTAMP:20260409T131010
CREATED:20211019T110456Z
LAST-MODIFIED:20211019T110532Z
UID:56282-1637578800-1637582400@www.h-its.org
SUMMARY:Colloquium Yuji Sugita: Parallel computing algorithms in molecular dynamics simulations for extremely large-scale biological systems
DESCRIPTION:  \nBy Yuji Sugita\, RIKEN\, Theoretical Molecular Science\, Japan \nMolecular dynamics (MD) simulations of nano- and biomolecules are one of the most important techniques in computational science. Protein conformational changes and protein-ligand bindings are simulated with all-atom MD simulations to elucidate molecular mechanisms underlying these biological processes. Conventionally\, we can perform MD simulations of a few proteins or nucleic acids in solution or in a phospholipid bilayer\, which mimics a biological membrane. These simulation systems typically contain 105 – 106 atoms in a simulation box and could be simulated using workstations or PC-clusters with/without GPGPUs. \nIf we need to study biological processes in more realistic cellular environments\, such as the cytoplasm\, cellular nuclei\, or realistic cell membranes\, we must simulate multiple biomolecules at the same time to consider their specific or non-specific molecular interactions. Then\, the size of a simulation system increases rapidly. One of our largest simulation systems to study macromolecular crowding effects in the cytoplasm contain 10 billion atoms\, which is hardly simulated with conventional MD software on the standard computational environments. \nIn our group\, we have developed high-performance MD software\, GENESIS\, (https://www.r-ccs.riken.jp/labs/cbrt/) for such large biological simulations. To improve the parallel computations\, we have implemented unique numerical techniques\, such as mid-point cell method\, volumetric decomposition of three-dimensional FFT calculations\, and so on. In my talk\, I will discuss several key algorithms in our software. In addition\, I discuss other key features of GENESIS\, such as enhanced sampling algorithms for slow conformational dynamics\, use of multi-scale models in MD simulations\, and so on. Using these computational techniques\, we can now study biomolecular structure\, dynamics\, and functions in realistic cellular environments to understand large-scale biological phenomena. For this purpose\, it is also important to incorporate experimental observations with computer simulations through machine learning or data-assimilation methods. We discuss a few examples of data-driven MD simulations of biomacromolecules. \n  \nCurriculum vitae: \nYuji Sugita is a chief scientist in Theoretical Molecular Science Laboratory at RIKEN Cluster for Pioneering Research\, in Wako\, Japan. He is also working as a team leader of two RIKEN centers\, such as RIKEN Center for Computational Science and RIKEN Center for Biosystems Dynamics Research\, in Kobe\, Japan. His research interest is the development and application studies of molecular dynamics simulations of biomolecules based on multi-scale models. He graduated from Department of Chemistry\, Graduate School of Kyoto University (1998) and received his Ph.D degree in Chemistry (1998). After a short postdoctoral fellow experience in RIKEN\, he moved to Institute for Molecular Science (IMS) in Japan as a research associate (1998) and wrote the first paper of replica-exchange molecular dynamics (REMD) simulation together with Prof. Yuko Okamoto. The paper (Chem. Phys. Lett. 314\, 141-151\, 1999) has been highly cited until now (4349 times in Google Scholar on October 14\, 2021). Then\, he moved to the Institute of Molecular and Cellular Biosciences\, University of Tokyo and started molecular dynamics simulation studies of Calcium Ion Pump with Prof. Chikashi Toyoshima. From 2007\, he has worked in RIKEN as a PI (associate chief scientist (2007-2012) and chief scientist (2012-present)). His research group has developed MD software GENESIS since 2009\, which is one of the target software in Co-design research of post-K supercomputer\, which becomes “Fugaku” supercomputer now. \n  \nREGISTRATION: \nThe colloquium is taking place via Zoom.\nPlease register in advance for this meeting: https://kta-email.zoom.us/meeting/register/tJ0uduGsqz4rH9MYn7oqn5hOsU05BE_e8I05\nAfter registering\, you will receive a confirmation email containing information about joining the meeting.\n\n\nIn case you are not able to attend\, you can watch the talk afterwards on the HITS YouTube channel: https://www.youtube.com/user/TheHITSters.
URL:https://www.h-its.org/event/colloquium-yuji-sugita/
LOCATION:Online
CATEGORIES:Colloquia,Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2021/10/Foto_Sugita.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20211018T110000
DTEND;TZID=Europe/Berlin:20211018T120000
DTSTAMP:20260409T131010
CREATED:20211007T092202Z
LAST-MODIFIED:20211022T081529Z
UID:55987-1634554800-1634558400@www.h-its.org
SUMMARY:Colloquium Warner Marzocchi: Model validation in natural hazard forecasting - a scientific perspective
DESCRIPTION:  \nBy Warner Marzocchi\, Unversity of Naples\, Federico II\, Italy \nScience is rooted in the concept that a model can be tested against independent observations and rejected when necessary. However\, the problem of model testing becomes formidable when we consider natural “open” systems. Owing to their scale\, complexity\, and openness to interactions within a larger environment\, most natural systems cannot be replicated in the laboratory\, and direct observations of their inner workings are always inadequate. These difficulties raise serious questions about the meaning and feasibility of “model validation” and have led to the pessimistic view that the outcome of natural processes in general cannot be accurately predicted by mathematical models (cit). \nIn this talk I discuss some efforts in seismology and volcanology to address the validation problem\, and the link with the current procedures of calibration and scoring of the models. The discussion emphasizes the importance of clarifying the probabilistic framework adopted for natural hazard forecasting\, which is aimed at quantifying the deep uncertainties that pervade the modeling of the processes. These uncertainties can be differentiated into three fundamental types: (1) the natural variability of the  systems\, usually represented as stochastic processes with parameterized distributions (aleatory variability); (2) the uncertainty in our knowledge of how systems operate and evolve\, often represented as subjective probabilities based on expert opinion (epistemic uncertainty); and (3) the possibility that our forecasts are wrong owing to behaviors of processes about which we are completely ignorant and\, hence\, cannot quantify in terms of probabilities (ontological error). Then\, I describe a probabilistic framework for hazard analysis\, which unifies the treatment of all three types of uncertainty. Within this framework\, a forecasting model is said to be complete only if it (a) fully characterizes the epistemic uncertainties in the model’s representation of aleatory variability and (b) can be unconditionally tested (in principle) against observations to identify ontological errors. Unconditional testability\, which is the key to model validation\, hinges on an experimental concept that characterizes hazard events in terms of exchangeable data sequences with well-defined frequencies. We illustrate the application of this unified probabilistic framework by describing experimental concepts for some real applications. \n  \nCurriculum vitae: \nWarner Marzocchi is professor of Geophysics and of Natural Hazard Forecasting at the\nUniversity of Naples Federico II\, and Scuola Superiore Meridionale. He has coordinated\, at\ndifferent levels\, many national\, european\, and international projects focused on short- and longterm earthquake and eruption forecasting and hazard assessment. He is member of the Academia\nEuropaea and author of more than 160 papers on journals listed in the Web of Science (H-index\n40 in WoS\, and 41 in SCOPUS). He graduated cum laude in Earth Sciences (1987) and received\nhis PhD degree in Physics (1992) at the Alma Mater Studiorum University of Bologna. He\nbecame associate professor in Physics of Volcanism at the Osservatorio Vesuviano\, and he has\nbeen visiting professor at the Institute of Statistical Mathematics in Tokyo\, visiting scientist at the\nUniversity of Southern California\, and chief scientist at the Istituto Nazionale di Geofisica e\nVulcanologia (INGV). He has served as chairman and member in many international scientific\norganizations\, co-chairman of the seismic hazard center at INGV\, and he has been member of the\nInternational Commission on Earthquake Forecasting (ICEF) appointed by the Italian government\nafter L’Aquila earthquake. He has been also invited to give lectures and talks at the major\ngeophysical meetings\, at many universities and research institutes in different countries. \n  \nThe colloquium on the HITS YouTube Channel: https://youtu.be/rUYkw3yPrDc
URL:https://www.h-its.org/event/colloquium-warner-marzocchi/
CATEGORIES:Colloquia,Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2021/10/Foto-Warner.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20210628T160000
DTEND;TZID=Europe/Berlin:20210628T170000
DTSTAMP:20260409T131010
CREATED:20210610T114838Z
LAST-MODIFIED:20210610T150924Z
UID:53252-1624896000-1624899600@www.h-its.org
SUMMARY:Colloquium Alán Aspuru-Guzik: There is no time for science as usual: Materials Acceleration Platforms
DESCRIPTION:By Alán Aspuru-Guzik\, Department of Chemistry and Department of Computer Science\, University of Toronto\, Canada \nThe world is facing several time-sensitive issues ranging from climate change to the rapid degradation of our climate\, as well as the emergence of new diseases like COVID-19. We need to rethink the way we do science and think of it as a workflow that could be optimized. Where are the pain points that can be solved with automation\, artificial intelligence\, or better human practices? My group has been thinking about this question with an application to the design of organic optoelectronic materials. In this talk\, I will discuss the progress in developing materials acceleration platforms\, or self-driving labs for this purpose. \nCurriculum vitae: \nAlán Aspuru-Guzik is a professor of Chemistry and Computer Science at the University of Toronto and is also the Canada 150 Research Chair in Theoretical Chemistry and a Canada CIFAR AI Chair at the Vector Institute. He is a CIFAR Lebovic Fellow in the Biologically Inspired Solar Energy program. Alán also holds an Google Industrial Research Chair in Quantum Computing. Alán is the director of the Acceleration Consortium\, a University of Toronto-based strategic initiative that aims to gather researchers from industry\, government and academia around pre-competitive research topics related to the lab of the future. \nAlán began his independent career at Harvard University in 2006 and was a Full Professor at Harvard University from 2013-2018. He received his B.Sc. from the National Autonomous University of Mexico (UNAM) in 1999 and obtained a PhD from the University of California\, Berkeley in 2004\, where he was also a postdoctoral fellow from 2005-2006. \nAlán conducts research in the interfaces of quantum information\, chemistry\, machine learning and chemistry. He was a pioneer in the development of algorithms and experimental implementations of quantum computers and quantum simulators dedicated to chemical systems. He has studied the role of quantum coherence in the transfer of excitonic energy in photosynthetic complexes and has accelerated the discovery by calculating organic semiconductors\, organic photovoltaic energy\, organic batteries and organic light-emitting diodes. He has worked on molecular representations and generative models for the automatic learning of molecular properties. Currently\, Alán is interested in automation and “autonomous” chemical laboratories for accelerating scientific discovery. \nAmong other recognitions\, he received the Google Focused Award for Quantum Computing\, the Sloan Research Fellowship\, The Camille and Henry Dreyfus Teacher-Scholar award\, and was selected as one of the best innovators under the age of 35 by the MIT Technology Review. He is a member of the American Physical Society and an elected member of the American Association for the Advancement of Science (AAAS) and received the Early Career Award in Theoretical Chemistry from the American Chemical Society. \nAlán is editor-in-chief of the journal Digital Discovery as well as co-founder of Zapata Computing and Kebotix. \n  \nREGISTRATION: \nThe colloquium is taking place via Zoom.\nPlease register in advance for this meeting:\nhttps://kta-email.zoom.us/meeting/register/tJMkc-mprT8tE9X5XIJDIYwBqaZvYvDd8CPU.\nAfter registering\, you will receive a confirmation email containing information about joining the meeting.\n\nIn case you are not able to attend\, you can watch the talk afterwards on the HITS YouTube channel: https://www.youtube.com/user/TheHITSters.
URL:https://www.h-its.org/event/colloquium-alan-aspuru-guzik/
LOCATION:Online
CATEGORIES:Colloquia,Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2021/06/Foto_Aspuru-Gudzik-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20210517T110000
DTEND;TZID=Europe/Berlin:20210517T120000
DTSTAMP:20260409T131010
CREATED:20210428T134751Z
LAST-MODIFIED:20210428T141758Z
UID:52669-1621249200-1621252800@www.h-its.org
SUMMARY:Colloquium Alina Schadwinkel: Science journalism in Corona times
DESCRIPTION:By Alina Schadwinkel\, Spektrum der Wissenschaft Verlagsgesellschaft mbH\, Heidelberg \nWhat the heck is a coronavirus ? How do I protect myself? How safe and effective are the new vaccines – and when will the pandemic finally be over? For more than a year\, Sars-CoV-2 has dominated the media. People are demanding information. As quickly as possible\, as precisely as possible. Presented neither downplaying nor alarmist. A challenge. \nSeldom has it been so important to communicate science well as in these times. It is true that the core task of science journalism is to report facts and thus provide orientation\, rather than to publish opinions and positions. But today\, false reports are spreading rapidly that in the past would never have been put into the world in the first place. \nWhat distinguishes good reporting? How can scientists and journalists work together? To what extent do social media and the 24/7 news cycle complicate the work? And what can we learn from last year’s reporting for other important issues like climate change? \nThis is what Alina Schadwinkel\, Managing Editor Online of Spektrum der Wissenschaft\, talks about and discusses with you. \n  \nCurriculum vitae: \nBorn in 1987\, studied science journalism with a focus on life sciences/medicine at TU Dortmund University. From 2009 to 2010 as a trainee at »ZEIT Online«\, then freelance for various media and ZEIT editor from 2011 to 2012. Until 2013 deputy head of the life sciences department of the »New Scientist«. Subsequently six weeks with the IJP in South Africa. From October 2013 to December 2019 as editor in the science department of “ZEIT Online” in Berlin. From then on\, Managing Editor Online of »Spektrum der Wissenschaft«. Winner of the Georg von Holtzbrinck Prize for Science Journalism 2014 in the category of young talent. Top 30 under 30 of the year 2015. Nominated for the Grimme Online Award in the same year for the dossier on Down’s syndrome »Wer darf Leben?«. 2016 shortlisted for the Ernst Schneider Award for the team project »Quantified Self«. 2019 nominated for the Salus Media Award as well as in the team for the Reporter Award in the category »Multimedia«. 2021 awarded the »Prize for Science Journalism» of the DGK. \n  \nREGISTRATION: \nThe colloquium is taking place via Zoom.\nPlease register in advance for this meeting:\nhttps://kta-email.zoom.us/meeting/register/tJ0pfuCrrT8oGtBigH0K3zZe9iW91CQ-cUzr\nAfter registering\, you will receive a confirmation email containing information about joining the meeting.\nIn case you are not able to attend\, you can watch the talk afterwards on the HITS YouTube channel: https://www.youtube.com/user/TheHITSters.\n 
URL:https://www.h-its.org/event/colloquium-alina-schadwinkel/
LOCATION:Online
CATEGORIES:Colloquia,Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2021/04/Foto_Alina-Schadwinkel-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20210426T150000
DTEND;TZID=Europe/Berlin:20210426T160000
DTSTAMP:20260409T131010
CREATED:20210324T080252Z
LAST-MODIFIED:20260126T095945Z
UID:52046-1619449200-1619452800@www.h-its.org
SUMMARY:Colloquium Lillian T. Chong: Weighted ensemble simulations of long-timescale dynamics: From chemical reactions to SARS-CoV-2
DESCRIPTION:By Lillian Chong\, Department of Chemistry\, University of Pittsburgh\, USA \n  \nThe weighted ensemble (WE) path sampling strategy orchestrates multiple simulations in parallel with rigorous statistical resampling at fixed time intervals to maintain rigorous kinetics. WE simulations can be orders of magnitude more efficient than standard simulations in generating unbiased\, atomically detailed pathways for rare events such as large conformational transitions in proteins and protein binding processes. The WE strategy can be applied at any scale with any type of stochastic dynamics engine – from ab initio simulations to cell-scale simulations and beyond. I will present our recent applications of the WE strategy as well as challenges that remain in tackling long-timescale kinetics. \n  \n  \nREGISTRATION: \nThe colloquium is taking place via Zoom. To receive the URL\, please register with Benedicta Frech\, Benedicta.Frech@h-its.org.\nIn case you are not able to attend\, you can watch the talk afterwards on the HITS YouTube channel: https://www.youtube.com/user/TheHITSters.
URL:https://www.h-its.org/event/colloquium-lillian-t-chong/
LOCATION:Online
CATEGORIES:Colloquia,Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2021/03/Foto_Lilian.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20210125T150000
DTEND;TZID=Europe/Berlin:20210125T160000
DTSTAMP:20260409T131010
CREATED:20210119T184021Z
LAST-MODIFIED:20260126T100003Z
UID:50733-1611586800-1611590400@www.h-its.org
SUMMARY:Colloquium Erin R. Johnson: Dispersion Interactions in Density-Functional Theory and Application to Molecular Crystal-Structure Prediction
DESCRIPTION:By Erin R. Johnson\, Department of Chemistry\, Department of Physics & Atmospheric Science\, Dalhousie University\, Halifax\, Canada \n  \nThe exchange-hole dipole moment (XDM) method is a density-functional model of London dispersion based upon second-order perturbation theory. The XDM dispersion coefficients are non-empirical and depend directly on the electron density and related properties\, allowing variation of the atomic dispersion coefficients with changing chemical environment. XDM offers simultaneous high accuracy for a diverse range of chemical systems\, including layered materials and metal surfaces. In this talk\, recent applications of XDM will be presented\, with a focus on molecular crystal-structure prediction (CSP). We will illustrate the utility of composite methods for CSP of chiral helicenes\, which have applications in organic electronics\, and of several pharmaceutical compounds. Finally\, the effect of the density-functional delocalisation error on CSP is highlighted for organic acid-base co-crystals. \n  \n  \nREGISTRATION: \nThe colloquium is taking place via Zoom. To receive the URL\, please register with Benedicta Frech\, Benedicta.Frech@h-its.org.\nAs we are not sure yet whether we will have the permission to record this colloqium\, we strongly recommend you watch it live.
URL:https://www.h-its.org/event/colloquium-erin-r-johnson/
LOCATION:Online
CATEGORIES:Colloquia,Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2021/01/Erin-Johnson-Foto.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20210120T160000
DTEND;TZID=Europe/Berlin:20210120T170000
DTSTAMP:20260409T131010
CREATED:20210104T104204Z
LAST-MODIFIED:20210113T092624Z
UID:50437-1611158400-1611162000@www.h-its.org
SUMMARY:Siobhan Roberts: Embracing the Uncertainties
DESCRIPTION:  \nIn her talk\, Siobhan Roberts will reflect on her pandemic reporting and the importance of uncertainty in science. She will discuss epistemic uncertainty\, a lack of knowledge about facts and numbers pertaining to the past and present\, versus aleatory uncertainty\, unknowns about the future due to randomness and chance. She will also explore the impact of Bayesian analysis on our own thinking\, putting up the question: Should we think like a Bayesian? \nAbout Siobhan Roberts \nSiobhan Roberts has worked as a freelance journalist with a focus on mathematics and science since 2001. She writes regularly for The New York Times “Science Times\,” and has contributed to The New Yorker’s science and tech blog “Elements\,” The Walrus\, Quanta and The Guardian\, among other publications. Moreover\, she is the author of two biographies of mathematicians: “King of Infinite Space” on Donald Coxeter\, and “Genius at Play” on John Horton Conway. She earned multiple awards for her work\, among them the Euler Book Prize from Mathematical Association of America. She is the ninth HITS “Journalist in Residence.” \nREGISTRATION: \nThe colloquium is taking place via Zoom. To receive the URL\, please register with Benedicta Frech at Admin.FO@h-its.org\nIn case you are not able to attend\, you can watch the talk afterwards on the HITS YouTube channel: https://www.youtube.com/user/TheHITSters.\n 
URL:https://www.h-its.org/event/talk-siobhan-roberts/
LOCATION:Online
CATEGORIES:Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2020/10/HITS_Siobhan_Roberts-1_web.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20201123T140000
DTEND;TZID=Europe/Berlin:20201123T150000
DTSTAMP:20260409T131010
CREATED:20201103T120216Z
LAST-MODIFIED:20260126T100014Z
UID:49350-1606140000-1606143600@www.h-its.org
SUMMARY:Colloquium Robert Best: Molecular Simulations of Intrinsically Disordered Proteins
DESCRIPTION:  \nBy Robert Best\, National Institute of Diabetes and Digestive and Kidney Diseases\, Theoretical Biophysical Chemistry Section\, USA \nIntrinsically disordered proteins are now recognized to play a variety of roles in biology\, yet are challenging to characterize by experiment owing to the diverse ensemble of structures they populate. This makes molecular simulations\, which can generate accurate models for disordered structures\, a natural complement to experiment. I describe here how data from simulation and experiment can be combined to yield the most likely distribution of unfolded states\, and how coarse grained simulation models can be parameterized to match available experimental data for complexes of disordered proteins. Lastly\, I will talk about our work using coarse-grained models to describe phase separation to form biomolecular coacervates. \n  \n  \nREGISTRATION: \nThe colloquium is taking place via Zoom. To receive the URL\, please register with Benedicta Frech\, Benedicta.Frech@h-its.org.\nIn case you are not able to attend\, you can watch the talk afterwards on the HITS YouTube channel: https://www.youtube.com/user/TheHITSters.\n 
URL:https://www.h-its.org/event/colloquium-robert-best/
LOCATION:Online
CATEGORIES:Colloquia,Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2020/11/Foto_Best-1-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20201012T110000
DTEND;TZID=Europe/Berlin:20201012T120000
DTSTAMP:20260409T131010
CREATED:20201008T111041Z
LAST-MODIFIED:20201008T112147Z
UID:49011-1602500400-1602504000@www.h-its.org
SUMMARY:Colloquium: Claudia Draxl: Predicting properties of complex materials: challenges for modern ab initio theory
DESCRIPTION:  \nProf. Dr. Claudia Draxl\, Physics Department of the Humboldt-University of Berlin\, solid-state theory group \n  \nCurriculum vitae:  \nClaudia Draxl is Einstein Professor at the Humboldt-Universität zu Berlin\, Germany and Max-Planck Fellow at the Max Planck Graduate Center for Quantum Materials. Her research interests cover theorectical concepts and methodology to get insight into a variety of materials and their properties. She is developer of the all-electron full-potential package exciting\, implementing density-functional theory (DFT) and methods beyond\, with a focus on excitations. A recently devloped package is the cluster-expansion code CELL. Actual research projects concern organic/inorganic hybrid structures\, wide-gap oxides\, thermoelectricity\, solar-cell materials\, film growth\, and more. She is one of the founders of the Novel Materials Discovery (NOMAD) Repository\, an open-access library of materials\, and the non-profit association FAIR-DI (FAIR Data Infrastructure for Physics\, Chemistry\, Materials Science\, and Astronomy). Based on this\, her data-driven research aims at finding structure in Big Data of materials science. \n  \nREGISTRATION: \nThe colloquium is taking place via Zoom. To receive the URL\, please register with Benedicta Frech\, Benedicta.Frech@h-its.org.\nIn case you are not able to attend\, you can watch the talk afterwards on the HITS YouTube channel: https://www.youtube.com/user/TheHITSters.
URL:https://www.h-its.org/event/colloquium-claudia-draxl/
CATEGORIES:Colloquia,Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2020/10/Photo-Draxl-1-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20200908T110000
DTEND;TZID=Europe/Berlin:20200908T120000
DTSTAMP:20260409T131010
CREATED:20200901T091509Z
LAST-MODIFIED:20200901T094559Z
UID:48266-1599562800-1599566400@www.h-its.org
SUMMARY:Colloquium Jens Meiler: Innovative Computational Methods for Protein Structure Prediction\, Drug Discovery\, and Therapeutic Design
DESCRIPTION:  \nProf. Dr. Jens Meiler\, Vanderbilt University\, Informatics Center for Structural Biology\, USA \n  \nCurriculum vitae:  \nJens Meiler studied Chemistry Leipzig University in Germany before he obtained his PhD working in the laboratory of Christian Griesinger at the Goethe University in Frankfurt developing new computational methods for biomolecular NMR spectroscopy. In 2001 he moved to Seattle to work with David Baker creating the protein modeling software Rosetta. In 2005 he joined the faculty at Vanderbilt University. In his research Dr. Meiler fuses computational and experimental efforts to investigate proteins\, the fundamental molecules of biology\, and their interactions with small molecule substrates\, therapeutics\, or probes. He develops computational methods with three major ambitions in mind: to enable protein structure elucidation of membrane proteins\, design proteins with novel structure and/or function\, and understand the relation between chemical structure and biological activity for drug-like small molecules. His research team in Nashville consists of around 30 undergraduate\, graduate\, and post-graduate students as well as staff scientists. He co-authored more than 200 peer-reviewed publications (H-index >40). Jens Meiler received several honors including the Chancellor Faculty Award at Vanderbilt University and the Friedrich-Wilhelm-Bessel Award of the Humboldt Foundation. In January 2020\, with an Alexander von Humboldt Professorship\, Jens Meiler became director of the newly founded Institute for Drug Discovery at Leipzig University. \n  \nREGISTRATION: \nThe colloquium is taking place via Zoom. To receive the URL\, please register with Benedicta Frech\, Benedicta.Frech@h-its.org.\nIn case you are not able to attend\, you can watch the talk afterwards on the HITS YouTube channel: https://www.youtube.com/user/TheHITSters.\n 
URL:https://www.h-its.org/event/colloquium-jens-meiler/
CATEGORIES:Colloquia,Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2020/09/Jens-Meiler.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20200629T110000
DTEND;TZID=Europe/Berlin:20200629T120000
DTSTAMP:20260409T131010
CREATED:20200609T105544Z
LAST-MODIFIED:20260126T100233Z
UID:46813-1593428400-1593432000@www.h-its.org
SUMMARY:Colloquium Robert C. Williamson: The AI of Ethics
DESCRIPTION:  \nProf. Dr. Robert C. Williamson\, Australian National University\, Research School of Computer Science\, Australia \nWith the rapid growth of AI and its deployment with consequences to people\, ethical concerns regarding AI have become extremely topical. In this talk I will present a view somewhat contrary relative to much of the current literature. After briefly summarising some of the ethical concerns\, I will argue that \n\nthe ethical problems of AI can be well understood\, and mitigations and progress can be made\, by recognising that AI\, as a technology shares many features with other older technologies;\nethical decisions have always been made using technologies;\nthe careful formulation of the problems to be solved is more important than immediately attempting to come up with solutions;\nin so doing new and valuable research directions in AI are opened up;\nmany of the problems ascribed to AI are more to do with the business models within which they are used; and\nwhile there are pressing problems that demand solving\, there are also many promising prospects for making real ethical progress with AI technologies as tools – it all depends upon the choices that we make.\n\n  \n  \nREGISTRATION: \nThe colloquium is taking place via Zoom. To receive the URL\, please register with Benedicta Frech\, Benedicta.Frech@h-its.org.\nIn case you are not able to attend\, you can watch the talk afterwards on the HITS YouTube channel: https://www.youtube.com/user/TheHITSters.
URL:https://www.h-its.org/event/colloquium-robert-c-williamson/
CATEGORIES:Colloquia,Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2020/06/bob2015-1-002.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20200217T110000
DTEND;TZID=Europe/Berlin:20200217T120000
DTSTAMP:20260409T131010
CREATED:20200123T090643Z
LAST-MODIFIED:20200203T095255Z
UID:42368-1581937200-1581940800@www.h-its.org
SUMMARY:Future Compute Paradigms
DESCRIPTION:By Wolfgang Maier\, Director HW Development\, IBM R&D – Systems & Technology Group\, Böblingen \nThe ongoing digitization of todays world is essentially based on Shannon’s theory of Information and its implementation by means of semiconductor cicuitry\, which is characterized by Moore’s law. The principal concept of this approach is to represent information by bits\, which stands for the\nminimum unit of information. With the advanced availabilty of digital data there is a growing expectation to extract more value from this data\, which in consequence means to deal with more complex abstractions of information\, respectively requires an enormous additional demand in traditional compute capacity. As physical limitations are inevitably confining the forward projection of Moore’s law new compute paradigms are essential to cope with the challenges arising from e.g. new applications in the field of Artificial Intelligence or from scientific issues in regard to Material Sciences. Brain inspired computing leveraging neurosynaptic approaches respectively quantum information processing using qBits as a complex representation of information represent such type of new compute paradigms.\nThe talk will give an overview of the current state of technology in respect to Moore’s law\, outline the underlying concepts of information theory and give insights on how those new compute paradigms are applied respectively implemented. \n  \nCurriculum vitae:  \nWolfgang Maier is Director Hardware Development at the german sited IBM R&D lab close to Stuttgart.\n\nHis career with IBM started as design engineer for Mainframe Firmware in 1996. 3 years later he accepted the role of department manager for System z IO Firmware and started to focus on the employment of industry standard IO technologies in IBM high end servers. During his international assignment in Austin (Tx) he directed the first implementation of the Infiniband technology for the IBM POWER line.\nAfter his return to Germany he extended the use of industry standards within the mainframe and headed the development of central IO hardware as well as mainframe and POWER CMOS processors.\nHis current responsibilities also span the system packaging and system control area with special focus on workload optimization and power efficiency. His current focus in innovation is on Artificial Intelligence and Quantum Computing.\nWolfgang Maier obtained his PhD in Laserphysics from the University of Tuebingen in 1996.\nHe enjoys to spend his spare time with his family\, loves skiing and motorbikes .\n  \nREGISTRATION: \nFor registration please contact Benedicta Frech: benedicta.frech@h-its.org \nIn case you are not able to attend in person\, you can watch the talk afterwards on the HITS YouTube channel: https://www.youtube.com/user/TheHITSters.\nThe colloquium will be live streamed\, please use the following link: https://hitsmediaweb.h-its.org/Mediasite/Play/1c4c408f1a0943cf9f540d2475d7ae7e1d
URL:https://www.h-its.org/event/future-compute-paradigms/
LOCATION:Studio Villa Bosch\, Schloss-Wolfsbrunnenweg 33\, Heidelberg\, 69118\, Germany
CATEGORIES:Colloquia,Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2020/01/Presentation-Picture.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20200127T110000
DTEND;TZID=Europe/Berlin:20200127T120000
DTSTAMP:20260409T131010
CREATED:20200108T134922Z
LAST-MODIFIED:20260126T100222Z
UID:42156-1580122800-1580126400@www.h-its.org
SUMMARY:Simulation of deep convective clouds under various meteorological and microphysical impacts
DESCRIPTION:By Prof. Dr. Corinna Hoose\, Institute of Meteorology and Climate Research\, Karlsruhe Institute of Technology \nDeep convective clouds and the resulting heavy precipitation\, hail\, lightning and wind gusts can cause severe damage. Their forecasting with current numerical weather prediction models is a challenge\, both because of limitations on spatial resolution and because of the low predictability of timing\, location and properties of the storms. In numerical simulations\, the impact of changes in meteorological (e.g. temperature\, wind) and in microphysical conditions (e.g. aerosol particles acting as cloud condensation nuclei\, strength of ice formation) can be investigated in sensitivity experiments\, and I will show results for different cases and different variables of interest. However\, for realistic cases\, such sensitivity experiments become very costly or not feasible at all. For some applications\, statistical emulation can be used as an approach to address this problem. \n  \nCurriculum vitae:  \n\nSeit 01/2013: Professorin (W3) für Theoretische Meteorologie am IMK-TRO \, Karlsruher Institut für Technologie (KIT)\n04/2010-10/2016: Helmholtz-Nachwuchsgruppenleiterin am IMK-AAF \, Karlsruher Institut für Technologie (KIT)\n06/2008-03/2010: Postdoktorandin\, University of Oslo \, Norwegen\, in der Gruppe von Jón Egill Kristjánsson \n03/2008-05/2008: Postdoktorandin\, IAC \, ETH Zürich\, Schweiz\, in der Gruppe von Ulrike Lohmann \n02/2005-02/2008: Doktorandin\, IAC\, ETH Zürich\, Schweiz\, in der Gruppe von Ulrike Lohmann\n10/1999-12/2004: Physikstudium\, Universität Karlsruhe (jetzt KIT)\n\n  \nREGISTRATION: \nFor registration please contact Benedicta Frech: benedicta.frech@h-its.org \nIn case you are not able to attend in person\, you can watch the talk afterwards on the HITS YouTube channel: https://www.youtube.com/user/TheHITSters.\nThe colloquium will be live streamed\, please use the following link: https://hitsmediaweb.h-its.org/Mediasite/Play/667b4ee2648a409e81cba714d230e7d01d
URL:https://www.h-its.org/event/colloquium-corinna-hoose/
LOCATION:Studio Villa Bosch\, Schloss-Wolfsbrunnenweg 33\, Heidelberg\, 69118\, Germany
CATEGORIES:Colloquia,Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2020/01/20160804-CN-04-01-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20191216T110000
DTEND;TZID=Europe/Berlin:20191216T120000
DTSTAMP:20260409T131010
CREATED:20191125T123642Z
LAST-MODIFIED:20260126T100246Z
UID:41453-1576494000-1576497600@www.h-its.org
SUMMARY:Integrative Modeling of Allosteric Modulation in Pentameric Ligand-Gated Ion Channels
DESCRIPTION:By Erik Lindahl\, Stockholms universitet\, Department of Biochemistry and Biophysics\, Stockholm\, Sweden \nLigand-gated ion channels control the electrical excitation of nerve cells\, in particular in the post-synaptic membrane in response to chemical signals mediated by neurotransmitters. These receptors exhibit an amazing diversity in detailed structure and function – some human channels have 15-20 slightly genes\, and with five subunits this can theoretically lead to almost a million different oligomers. They are further characterised by adopting both closed\, open and desensitised states – and in addition to the neurotransmitters causing normal opening they are subject to secondary control – allosteric modulation – by a number of drugs such as alcohols\, benzodiazepines\, neurosteroids\, and anaesthetics that either potentiate or inhibit the agonist response. I will present our work on understanding the molecular mechanisms of these channels by using a broad range of experimental and theoretical methods\, and illustrate that while each method has many shortcomings their combination increasingly enable us to capture different timescales\, features\, interactions and not least dynamics of important membrane proteins. For ligand-gated ion channels in particular\, I will illustrate how this is enabling us to explain several key mechanisms\, including identifying the separate potentiating and inhibitory binding sites\, showing how we can reverse the allosteric modulation of specific channels\, to propose detailed functional models even from intermediate-resolution structural data – and not least start to understand the critical interplay of how lipids modulate membrane protein function. \n  \n  \nREGISTRATION: \nFor registration please contact Benedicta Frech: benedicta.frech@h-its.org \nIn case you are not able to attend in person\, you can watch the talk afterwards on the HITS YouTube channel: https://www.youtube.com/user/TheHITSters.\nThe colloquium will be live streamed\, please use the following link: https://hitsmediaweb.h-its.org/Mediasite/Play/304530a014b24e9d9154a06856cc888e1d
URL:https://www.h-its.org/event/colloquium-erik-lindahl/
CATEGORIES:Colloquia,Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2019/11/Lindahl.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20191203T200000
DTEND;TZID=Europe/Berlin:20191203T220000
DTSTAMP:20260409T131010
CREATED:20191121T145249Z
LAST-MODIFIED:20191121T145417Z
UID:41484-1575403200-1575410400@www.h-its.org
SUMMARY:HITS at “Astronomy on Tap”
DESCRIPTION:“Can crowdsourcing be replaced by machine learning” – the pub talk by HITS researcher Erica Hopkins from the Astroinformatics (AIN) group. \nThe event is held in O’Reilly’s Irish Pub on Brückenkopfstraße (just across the river from Bismarckplatz). Entrance is free!\n \n“Astronomy on Tap” is a series of monthly astronomy events held in Heidelberg. Each event features two fun talks by professional astronomers telling the audience about the cool science they do. There’s also a daft astronomy quiz that requires no prior knowledge.
URL:https://www.h-its.org/event/astronomy-on-tap-12-2019/
CATEGORIES:Public Events
ATTACH;FMTTYPE=image/png:https://www.h-its.org/wp-content/uploads/2019/11/Astronomy_on_Tap.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20191118T110000
DTEND;TZID=Europe/Berlin:20191118T120000
DTSTAMP:20260409T131010
CREATED:20191010T082929Z
LAST-MODIFIED:20191114T095059Z
UID:40444-1574074800-1574078400@www.h-its.org
SUMMARY:Colloquium Keith A. Crandall: Computational Approaches for Characterizing Microbiome Diversity
DESCRIPTION:By Keith A. Crandall\, PhD\, Professor ob Biostatistics & Bioinformatics\, Director – Computational Biology Institute\, Milken Institute School of Public Health\, George Washington University\, Washington\, DC\, USA \n  \nMicrobiome characterization has become an integral component to the study of a wide variety of disease and health for a diversity of organisms. Through the collection of metagenomic sequence data from DNA and/or RNA samples isolated from host individuals\, effective microbiome characterization can identify pathogens\, link diversity to disease state\, characterize treatment effects\, and identify drug resistant variants. I present a computational platform\, PathoScope\, for metagenomic sequence analysis to characterize microbiome diversity and test hypotheses about diversity associates with disease and diversity dynamics over time. I then describe a second software package\, TeleScope\, that characterizes transposable elements in genomic data (a part of the microbiome component often ignored)\, maps those elements back to reference genomes\, and identifies active mobile elements and their potential phenotypic impact. I present results from both empirical studies and simulation studies characterizing the utility of our computational approaches with metagenomic data and compare our approach to other leading packages. I then demonstrate our computational tools with applications in endangered species conservation\, agriculture\, and a variety of aspects of human health. Specifically\, I will demonstrate the use of microbiome characterization related to black rhino health\, human health related to Konzo disease\, and human fecal transplant diversity over time. Finally\, I will demonstrate the characterization of human endogenous retroviral elements (HERVs) in relation to head and neck cancer and incorporate this information into risk assessment. \n  \nCurriculum vitae: \nKeith A. Crandall\, PhD is the Founding Director of the Computational Biology Institute and Professor in the Department of Biostatistics and Bioinformatics at George Washington University. Professor Crandall studies the computational biology\, population genetics\, and bioinformatics\, developing and testing methods for DNA sequence analysis. He applies such methods to the study of the evolution of both infectious diseases (especially microbiome diversity) and crustaceans (especially Decapod crustaceans). Professor Crandall has published over 300 peer reviewed publications\, as well as three books. He has been a Fulbright Visiting Scholar to Oxford University and an Allen Wilson Centre Sabbatical Fellow at the University of Auckland. Professor Crandall has received a number of awards for research and teaching\, including the American Naturalist Society Young Investigator Award\, an NSF CAREER Award\, a PhRMA Foundation Faculty Development Award in Bioinformatics\, Honors Professor of the Year award at Brigham Young University\, ISI Highly Cited Researcher\, and the Edward O. Wilson Naturalist Award. He is an elected Fellow in the American Association for the Advancement of Science (AAAS) and a Fellow of the Linnean Society of London. Professor Crandall earned his BA degree from Kalamazoo College in Biology and Mathematics\, an MA degree from Washington University in Statistics\, and a PhD from Washington University School of Medicine in Biology and Biomedical Sciences. He also served as a Peace Corps Volunteer in Puyo\, Ecuador. \n  \nREGISTRATION: \nFor registration please contact Benedicta Frech: benedicta.frech@h-its.org \nIn case you are not able to attend in person\, you can watch the talk afterwards on the HITS YouTube channel: https://www.youtube.com/user/TheHITSters.\nThe colloquium will be live streamed\, please use the following link: https://hitsmediaweb.h-its.org/Mediasite/Play/38f46c0cc6a04bf09aa74b955894fe531d\n\n 
URL:https://www.h-its.org/event/colloquium-keith-a-crandall/
LOCATION:Studio Villa Bosch\, Schloss-Wolfsbrunnenweg 33\, Heidelberg\, 69118\, Germany
CATEGORIES:Colloquia,Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2019/10/Keith-Crandall.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20191112T200000
DTEND;TZID=Europe/Berlin:20191112T220000
DTSTAMP:20260409T131010
CREATED:20191106T123200Z
LAST-MODIFIED:20191106T123236Z
UID:41183-1573588800-1573596000@www.h-its.org
SUMMARY:HITS at "Astronomy on Tap"
DESCRIPTION:  \n“A New Science is Born: Astronomy in the Era of AI” – the pub talk by HITS researcher Antonio D’Isanto from the Astroinformatics (AIN) group. \nThe event is held in O’Reilly’s Irish Pub on Brückenkopfstraße (just across the river from Bismarckplatz). Entrance is free!\n \n“Astronomy on Tap” is a series of monthly astronomy events held in Heidelberg. Each event features two fun talks by professional astronomers telling you about the cool science they do. There’s also a daft astronomy quiz that requires no prior knowledge.
URL:https://www.h-its.org/event/astronomy-on-tap-11-2019/
CATEGORIES:Public Events
ATTACH;FMTTYPE=image/jpeg:https://www.h-its.org/wp-content/uploads/2019/11/Astronomy_on_Tap.jpg
END:VEVENT
END:VCALENDAR