Ariane Nunes-Alves

ResearchGate

ORCID

Research Interests

• Kinetics and thermodynamics of ligand-protein binding
• Molecular modeling and simulation of protein conformational transitions

Employment

• 2018 – present: postdoctoral researcher, Heidelberg Institute for Theoretical Studies, Germany

Education

• 2017 – PhD in Biochemistry, University of São Paulo, Brazil (dissertation)
  
• 2013 – MSc in Biochemistry, University of São Paulo, Brazil (thesis)
• 2010 – BSc in Biology, University of São Paulo, Brazil

Publications

• Nunes-Alves, A.; Zuckerman, D.M.; Arantes, G.M. Escape of a small molecule from inside T4 lysozyme by multiple pathways. Biophys. J., 114: 1058-1066, 2018.
  

• Nunes-Alves, A.; Arantes, G.M. Mechanical unfolding of macromolecules coupled to bond dissociation. J. Chem. Theory Comput., 14: 282-290, 2018.

• Nunes-Alves, A.; Arantes, G.M. Ligand-receptor affinities computed by an adapted linear interaction model for continuum electrostatics and by protein conformational averaging. J. Chem. Inf. Model.,54: 2309-2319, 2014.

• Nunes-Alves, A.; Nery, A.A.; Ulrich, H. Tobacco nitrosamine N-nitrosonornicotine as inhibitor of neuronal nicotinic acetylcholine receptors. J. Mol. Neurosci., 49: 52-61, 2013.

• Yuahasi, K.K.; Gomes, K.N.; Campos, M.; Nery, A.A.; Nunes-Alves, A.; Trujillo, C.A.; Ulrich, H. Neurotransmitters as main players in the neural differentiation and fate determination game. In: Henning Ulrich. (Org.). Perspectives of stem cells – From tools for studying mechanisms of neuronal differentiation towards therapy. Dordrecht Heidelberg London Ne: Springer Science + Business Media, ISBN 978-90-481-3374-1, p. 115-134, 2010.

Awards (selected)

• Travel award from the Biophysical Society (2014)
• Travel award from the Institute of Chemistry, University of São Paulo (2013)
• Best poster presentation in the area of Computational Biochemistry at the XLII Annual Meeting of the Brazilian Society for Biochemistry and Molecular Biology (2013)
• Travel award from the Society for Research on Nicotine and Tobacco – Europe (2010)
• Best poster presentation in the area of Ion Channels and Transporters at the XXIV Annual Meeting of the Federation of Societies for Experimental Biology (2009)