Group Leader and Scientific Director

Wolfgang Müller leads the Scientific Databases and Visualisation Group at HITS. He is Privatdozent at the Department for Business Informatics and Applied Informatics at the Universität Bamberg.

1996 he obtained a Diploma degree in physics at the University of Constance, with experimental work on soap foams at the CNRS Institute Charles Sadron at Strasbourg. He studied Computer Science in parallel at the FernUni Hagen. He obtained his diploma with a diploma thesis about data mining. 2001 he obtained a doctorat es sciences in Geneva (Prof. Dr. Thierry Pun), with work on Content Based Image Retrieval, i.e. finding images by their visual content. In 2008 he obtained a Habilitation degree at the University of Bamberg (2008) with work about Peer-to-Peer Information Retrieval, i.e. working on similarity search in distributed self-organising systems. Since 2008 Wolfgang Müller has been working at HITS, first as deputy group leader, then as successor of HITS Fellow Dr. Isabel Rojas (1968-2013), who had founded the group in 1999.

SDBV creates, populates and maintains data base applications, mostly for the use in systems biology. System biology strives to reach a systems understanding of biological systems. The challenges that SDBV addresses range from data integrations and efficient data structures to Human Computer Interaction, as well as social aspects of Open Data.

Müller has been coordinator of the data management of the systems biology Großprojekt (large project) Virtual Liver Network, and is data management coordinator of the currently running LiSyM (Liver SystemsMedicine) Großprojekt. He is also HITS’ delegate in transnational life sciences infrastructure initiatives as FAIRDOM, ISBE, and ELIXIR.

Publications

2019

  • Carolina B. Moraes, Gesa Witt, Maria Kuzikov, Bernhard Ellinger, Theodora Calogeropoulou, Kyriakos C. Prousis, Stefano Mangani, Flavio Di Pisa, Giacomo Landi, Lucia Dello Iacono, Cecilia Pozzi, Lucio H. Freitas-Junior, Bruno dos Santos Pascoalino, Claudia P. Bertolacini, Birte Behrens, Oliver Keminer, Jennifer Leu, Markus Wolf, Jeanette Reinshagen, Anabela Cordeiro-da-Silva, Nuno Santarem, Alberto Venturelli, Stephen Wrigley, Deepa Karunakaran, Bethlehem Kebede, Ina Pöhner, Wolfgang Müller, Joanna Panecka-Hofman, Rebecca C. Wade, Martina Fenske, Joachim Clos, José María Alunda, María Jesús Corral, Elisa Uliassi, Maria Laura Bolognesi, Pasquale Linciano, Antonio Quotadamo, Stefania Ferrari, Matteo Santucci, Chiara Borsari, Maria Paola Costi, Sheraz Gul (2019). Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform, SLAS DISCOVERY: Advancing the Science of Drug Discovery 24(3):346-361 1075

2018

2017

  • Pasquale Linciano, Alice Dawson, Ina Pöhner, David M. Costa, Monica S. Sá, Anabela Cordeiro-da-Silva, Rosaria Luciani, Sheraz Gul, Gesa Witt, Bernhard Ellinger, Maria Kuzikov, Philip Gribbon, Jeanette Reinshagen, Markus Wolf, Birte Behrens, Véronique Hannaert, Paul A. M. Michels, Erika Nerini, Cecilia Pozzi, Flavio di Pisa, Giacomo Landi, Nuno Santarem, Stefania Ferrari, Puneet Saxena, Sandra Lazzari, Giuseppe Cannazza, Lucio H. Freitas-Junior, Carolina B. Moraes, Bruno S. Pascoalino, Laura M. Alcântara, Claudia P. Bertolacini, Vanessa Fontana, Ulrike Wittig, Wolfgang Müller, Rebecca C. Wade, William N. Hunter, Stefano Mangani, Luca Costantino, Maria P. Costi (2017). Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery, ACS Omega 2(9):5666-5683 270
  • U. Wittig, M. Rey, A. Weidemann, W. Muller (2017). Data management and data enrichment for systems biology projects., J Biotechnol. 2017 Nov 10;261:229-237. doi: 10.1016/j.jbiotec.2017.06.007. Epub 2017 Jun 10. 17
  • Katherine Wolstencroft, Olga Krebs, Jacky L. Snoep, Natalie J. Stanford, Finn Bacall, Martin Golebiewski, Rostyk Kuzyakiv, Quyen Nguyen, Stuart Owen, Stian Soiland-Reyes, Jakub Straszewski, David D. van Niekerk, Alan R. Williams, Lars Malmström, Bernd Rinn, Wolfgang Müller, Carole Goble (2017). FAIRDOMHub: a repository and collaboration environment for sharing systems biology research, Nucleic Acids Res 45(D1):D404-D407 9

2016

  • David Nickerson, Koray Atalag, Bernard de Bono, Jörg Geiger, Carole Goble, Susanne Hollmann, Joachim Lonien, Wolfgang Müller, Babette Regierer, Natalie J. Stanford, Martin Golebiewski, Peter Hunter (2016). The Human Physiome: how standards, software, and innovative service infrastructures are providing the building blocks to make it achievable., Interface Focus 6(2):20150103 200
  • O. Krebs, K. Wolstencroft, NJ. Stanford, N. Morrison, M. Golebiewski, S. Owen, Q. Nguyen, JL. Snoep, W. Müller, C. Goble (2016). FAIRDOM approach for semantic interoperability of systems biology data and models., Proceedings International Conference on Biomedical Ontology, ICBO 2015. no. CEUR Workshop Proceedings 1515 199

2015

2014

2013

2011

  • R. J. Assef, K. D. Denney, C. S. Kochanek, B. M. Peterson, S. Kozłowski, N. Ageorges, R. S. Barrows, P. Buschkamp, M. Dietrich, E. Falco, C. Feiz, H. Gemperlein, A. Germeroth, C. J. Grier, R. Hofmann, M. Juette, R. Khan, M. Kilic, V. Knierim, W. Laun, R. Lederer, M. Lehmitz, R. Lenzen, U. Mall, K. K. Madsen, H. Mandel, P. Martini, S. Mathur, K. Mogren, P. Mueller, V. Naranjo, A. Pasquali, K. Polsterer, R. W. Pogge, A. Quirrenbach, W. Seifert, D. Stern, B. Shappee, C. Storz, J. Van Saders, P. Weiser, D. Zhang (2011). Black Hole Mass Estimates Based on C IV are Consistent with Those Based on the Balmer Lines, ApJ 742(2):93 453
  • U. Wittig, R. Kania, M. Golebiewski, M. Rey, L. Shi, L. Jong, E. Algaa, A. Weidemann, H. Sauer-Danzwith, S. Mir, O. Krebs, M. Bittkowski, E. Wetsch, I. Rojas, W. Muller (2011). SABIO-RK–database for biochemical reaction kinetics., Nucleic Acids Res. 2012 Jan;40(Database issue):D790-6. doi: 10.1093/nar/gkr1046. Epub 2011 Nov 18. 8
  • A. Pasquali, A. Bik, S. Zibetti, N. Ageorges, W. Seifert, W. Brandner, H.-W. Rix, M. Jütte, V. Knierim, P. Buschkamp, C. Feiz, H. Gemperlein, A. Germeroth, R. Hofmann, W. Laun, R. Lederer, M. Lehmitz, R. Lenzen, U. Mall, H. Mandel, P. Müller, V. Naranjo, K. Polsterer, A. Quirrenbach, L. Schäffner, C. Storz, P. Weiser (2011). Infrared Narrowband Tomography of the Local Starburst NGC 1569 with the Large Binocular Telescope/LUCIFER., The Astronomical Journal 141(4):132 454
  • Wolfgang Müller, Isabel Rojas, Andreas Eberhart, Peter Haase, Michael Schmidt (2011). A-R-E: The Author-Review-Execute Environment, Procedia Computer Science 4:627-636 16

2010

  • N. Swainston, M. Golebiewski, H. L. Messiha, N. Malys, R. Kania, S. Kengne, O. Krebs, S. Mir, H. Sauer-Danzwith, K. Smallbone, A. Weidemann, U. Wittig, D. B. Kell, P. Mendes, W. Muller, N. W. Paton, I. Rojas (2010). Enzyme kinetics informatics: from instrument to browser., FEBS J. 2010 Sep;277(18):3769-79. doi: 10.1111/j.1742-4658.2010.07778.x. Epub 2010 Aug 3. 18
  • Markus Wirtz, Hannah Birke, Corinna Heeg, Christopher Müller, Fabian Hosp, Christian Throm, Anna Feldman-Salit, Karsten Rippe, Gabriele Petersen, Rebecca C. Wade, Vladimir Rybin, Klaus Scheffzek, Ruediger Hell (2010). Structure and function of the hetero-oligomeric cysteine synthase complex in plants., J. Biol. Chem. 285(43):32810-32817 668

2004

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