In drug discovery it is often difficult to predict if a potential drug will be effective in humans. Recent studies have shown that the kinetics of the interaction between a drug and its target has a strong influence on the clinical success of a drug. “Kinetics for Drug Discovery” (K4DD) brings together experts from seven European countries. They focus on optimizing binding kinetics for drug candidates with the ultimate goal of improving drug design. K4DD was launched by the Innovative Medicines Initiative (IMI), the world’s largest public-private partnership in healthcare. Coordinators are Bayer HealthCare and Leiden University of the Netherlands. HITS researchers from the Molecular and Cellular Modeling group (head: Rebecca Wade) are among the 20 partners.
IMI is the world’s largest public-private partnership in healthcare. IMI is improving the environment for pharmaceutical innovation in Europe by engaging and supporting networks of industrial and academic experts in collaborative research projects. The research leading to these results has received support from the Innovative Medicines Initiative Joint Undertaking under grant agreement n° 115366, resources of which are composed of financial contribution from the European Union’s Seventh Framework Program (FP7/2007-2013) and EFPIA companies’ in kind contribution.
Dr. Peter Saueressig
Head of Communications
Heidelberg Institute for Theoretical Studies (HITS)
The Heidelberg Institute for Theoretical Studies (HITS) was established in 2010 by the physicist and SAP co-founder Klaus Tschira (1940-2015) and the Klaus Tschira Foundation as a private, non-profit research institute. HITS conducts basic research in the natural sciences, mathematics and computer science, with a focus on the processing, structuring, and analyzing of large amounts of complex data and the development of computational methods and software. The research fields range from molecular biology to astrophysics. The shareholders of HITS are the HITS-Stiftung, which is a subsidiary of the Klaus Tschira Foundation, Heidelberg University and the Karlsruhe Institute of Technology (KIT). HITS also cooperates with other universities and research institutes and with industrial partners. The base funding of HITS is provided by the HITS Stiftung with funds received from the Klaus Tschira Foundation. The primary external funding agencies are the Federal Ministry of Education and Research (BMBF), the German Research Foundation (DFG), and the European Union.