Issue 4 | 2025

10. December 2025

This year, the Heidelberg Laureate Forum once again offered 200 early-career researchers the opportunity to engage with leading laureates in mathematics and computer science. HITS participated as a scientific partner, giving a short showcase talk and hosting a booth.

In September 2025, Vagrant Gautam joined HITS as an Independent Postdoc. Vagrant works with the Natural Language Processing (NLP) group, focusing in particular on developing linguistically informed methods for reference resolution and the use of pronouns.

HITS group leader Alexandros Stamatakis is celebrating a special milestone this year: for the tenth consecutive year, he has been named a “Highly Cited Researcher,” once again ranking among the world’s top scientists in biology and biochemistry.

In July 2025, researchers at HITS, in collaboration with the Max Planck Institute for Polymer Research, developed the machine learning model FliPS, which enables targeted design of flexible proteins. Recently, they also introduced BBFlow, which reliably predicts the dynamics of these molecules. Together, FliPS and BBFlow form a powerful duo, making de novo protein design faster and more precise, and opening up promising opportunities for medicine and technology.

Australian science journalist Jackson Ryan spent six months at HITS as the 13th “Journalist in Residence.” In an interview, he shares his most memorable experiences at the institute and reveals what plans await him after his six-month stay.

We hope you enjoy reading and wish you a peaceful Advent season!

About HITS

HITS, the Heidelberg Institute for Theoretical Studies, was established in 2010 by physicist and SAP co-founder Klaus Tschira (1940-2015) and the Klaus Tschira Foundation as a private, non-profit research institute. HITS conducts basic research in the natural, mathematical, and computer sciences. Major research directions include complex simulations across scales, making sense of data, and enabling science via computational research. Application areas range from molecular biology to astrophysics. An essential characteristic of the Institute is interdisciplinarity, implemented in numerous cross-group and cross-disciplinary projects. The base funding of HITS is provided by the Klaus Tschira Foundation.

Switch to the German homepage or stay on this page