MBM Group
Molecular Biomechanics

Projects

Current Projects

Mechanoradicals in Collagen

24. February 2021

It has been known for many decades that synthetic polymers subjected to mechanical stress generate mechanoradicals by rupture of chemical bonds. …

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Mechanokinases

24. February 2021

Kinases are abundantly present in all cells and involved in the regulation of many important processes, such as cell survival, growth, …

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Force-triggered blood coagulation

30. January 2021

Von Willebrand factor (VWF) is a giant multidomain extracellular blood protein in charge of a key adhesive process during hemostasis: the …

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Force distribution analysis (FDA)

30. October 2014

Force distribution analysis (FDA) is a method to detect and follow force and stress propagation in proteins, reminiscent of Finite Element …

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Previous Projects

Mechanical properties of silk

18. December 2014

Silk is one of the many biomaterials with mechanical properties not yet reached by synthetic counterparts. Silk fibers have an outstanding …

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Mechanical properties of Nacre

2. December 2014

Nacre, also known as mother-of-pearl, is a biocomposite located at the inner layer of seashells, with exceptional mechanical properties such as …

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Structure-based Drug design

14. November 2014

Structure-based design methods have proven effective in every aspect of drug design – from lead discovery, development, through guiding clinical trials. …

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Force-driven allostery in proteins

11. November 2014

Allostery in proteins plays a significant role such as cell signalling or gene and enzyme regulations. Allostery is characterized by a …

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Mechano(bio)chemistry

30. October 2014

Chemical and enzymatic reactions can be guided by mechanical stress. While single molecule force spectroscopy is an emerging technique to study …

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