MCM Group

Projects

Our main aim is to develop and apply computer-aided methods to model, simulate and predict how biomolecules interact. The focus is on the interactions of proteins. The methods make use of three-dimensional macromolecular structures and combine approaches based on physicochemical principles with those of chemo- and bio-informatics.
Some of our projects are described on this page.

Structure-based drug discovery

14 01 2015

Proteins are dynamic and constantly changing their shape. This flexibility not only presents a challenge to to structure-based drug design approaches …

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Macromolecular interactions and diffusional association

14 01 2015

We are developing methods to predict protein-protein interactions and how proteins bind to surfaces. These methods rely on Brownian dynamics simulation …

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Protein structures in systems biology

14 01 2015

We are working on developing approaches to bridge between protein structures and biochemical networks, from the molecular to the cellular level….

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Gallery

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