MBM Group
Molecular Biomechanics

News

FAK allosteric network helps interpreting FRET measurements!

12. January 2015

Jing’s allosteric network of focal adhesion kinase (FAK) when binding PIP2 helped to interpret recent FRET results in FAK activation …

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Welcome Katra!

11. January 2015

Dr. Katra Kolsek joins us as a postdoc to work on disulfides in the von Willebrand factor. Welcome!

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Welcome Ana!

11. January 2015

We are happy that Ana Herrera Rodriguez joins us as a PhD student to work on silk assembly under flow. Welcome!

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Mechanosensing ability of Focal Adhesion Kinase

10. December 2014

Mechanosensing plays a decisive role at focal adhesions (Fas), sites at which external forces are integrated into cellular signaling pathways, thereby …

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Composite Materials

2. December 2014

Polymeric materials show outstanding mechanical properties and have attracted a great deal of scientific interest. By means of all-atom molecular dynamics, …

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Focal Adhesion Kinase is a mechanosensor!

2. December 2014

MD simulations of a FAK fragment containing the catalytic and FERM domains in different protein system are carried out to compare …

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Job

Proteins under shear flow

30. November 2014

Shear flow, as it occurs for example in blood vessel, is an alternative way of subjecting proteins to forces for signalling …

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Extremely elastic proteins

24. November 2014

The ultimate properties of proteins with respect to their ability to be force-reactive, are coarsely described by their capacity to withstand …

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Interaction between intrinsically disordered proteins and structured partners

24. November 2014

On the line of maturing new understanding of the factors regulating the correct dynamics of intrinsically disordered proteins in solution, one …

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Conformational dynamics of intrinsically disordered proteins

24. November 2014

Intrinsically disordered proteins (IDPs) lack, by definition, of a well-defined three-dimensional structure and therefore explore a much larger conformational ensemble with …

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