Made by nature: a highly elastic pressurized balloon

Collagens constitute the dominant class of extracellular proteins in multicellular organisms. They are highly abundant wherever high elasticity is needed. The collagens of cnidarians, multicellular organisms among the oldest appearing on Earth and including jellyfish and sea anemones, are particularly fascinating. They structure the wall of the nematocyst, a balloon-shaped organelle, designed to naturally withstand…

Universum: Simulationen am Supercomputer

This text is only available in German. Davon träumt die Wissenschaft: An einem Computer zu simulieren, wie sich das Universum bis heute entwickelt hat. Forscher aus Würzburg und Heidelberg wollen dem Traum jetzt näher kommen: Sie haben Rechenzeit im Wert von knapp fünf Millionen Euro auf einem Supercomputer bewilligt bekommen. Der Würzburger Mathematiker Professor Christian…

Spindle pole body bridge on the front cover

HITS scientists Musa Özboyaci and Prof. Rebecca Wade (MCM group) have performed calculations that help to understand the process of cell division in yeast. In a multidisciplinary study conducted together with researchers at the Center for Molecular Biology of Heidelberg University (ZMBH) and at Frankfurt University, the team led by Prof. Elmar Schiebel (ZMBH) revealed…

How Human Cells Can Dissolve Damaging Protein Aggregates

Heidelberg researchers decode fundamental mechanism using in-vitro experiments Cellular repair systems can dissolve aggregated proteins and now Heidelberg researchers have successfully decoded the fundamental mechanism that is key to dissolving these protein aggregates in human cells. Their in-vitro experiments uncovered a multi-stage biochemical process in which protein molecules are dissolved from the aggregates. Researchers at…