MBM Gruppe
Molecular Biomechanics

Projekte

Aktuelle Projekte

Emulation in simulation

28.06.2021

„Emulation in Simulation“ verbindet die HITS-Expertise in computergestützter Statistik und numerischer Simulation, um eine neue Generation von Werkzeugen für …

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Mechanokinases

12.03.2021

Kinases are abundantly present in all cells and involved in the regulation of many important processes, such as cell survival, growth, …

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Mechanoradicals in Collagen

12.03.2021

It has been known for many decades that synthetic polymers subjected to mechanical stress generate mechanoradicals by rupture of chemical bonds. …

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Intrinsically disordered Proteins

12.03.2021

Intrinsically disordered proteins (IDPs) are a new class of proteins that lack secondary and tertiary structures and instead explore a broad …

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Force-triggered blood coagulation

30.01.2020

Von Willebrand factor (VWF) is a giant multidomain extracellular blood protein in charge of a key adhesive process during hemostasis: the …

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Abgeschlossene Projekte

Beeinflusst der Schreibstil die Wirkung wissenschaftlicher Texte?

28.06.2021

Die Bedeutung und Qualität neuer Forschungsergebnisse in einem wissenschaftlichen Artikel wird oft dadurch gemessen, wie häufig dieser Artikel zitiert …

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Force distribution analysis (FDA)

30.01.2020

Force distribution analysis (FDA) is a method to detect and follow force and stress propagation in proteins, reminiscent of Finite Element …

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Mechanical properties of silk

18.12.2014

Silk is one of the many biomaterials with mechanical properties not yet reached by synthetic counterparts. Silk fibers have an outstanding …

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Mechanical properties of Nacre

2.12.2014

Nacre, also known as mother-of-pearl, is a biocomposite located at the inner layer of seashells, with exceptional mechanical properties such as …

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Structure-based Drug design

14.11.2014

Structure-based design methods have proven effective in every aspect of drug design – from lead discovery, development, through guiding clinical trials. …

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Force-driven allostery in proteins

11.11.2014

Allostery in proteins plays a significant role such as cell signalling or gene and enzyme regulations. Allostery is characterized by a …

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Mechano(bio)chemistry

30.10.2014

Chemical and enzymatic reactions can be guided by mechanical stress. While single molecule force spectroscopy is an emerging technique to study …

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